CXCL8
CXCL8，即C-X-C基序趨化因子配體8，別名IL-8、NAP-1、MDNCF。它是一種由多種細(xì)胞如中性粒細(xì)胞、單核細(xì)胞、巨噬細(xì)胞、T細(xì)胞、上皮細(xì)胞和內(nèi)皮細(xì)胞產(chǎn)生的趨化因子。CXCL8的作用機(jī)制主要是通過(guò)與其受體CXCR1和CXCR2結(jié)合，激活多個(gè)細(xì)胞內(nèi)信號(hào)通路，包括絲裂原活化蛋白激酶（MAPK）、磷酸肌醇-3激酶（PI3K）和蛋白激酶C（PKC）等，從而吸引中性粒細(xì)胞、嗜堿性粒細(xì)胞和T細(xì)胞到炎癥部位，清除病原體，協(xié)調(diào)炎癥反應(yīng)。CXCL8在炎癥反應(yīng)、腫瘤發(fā)展以及免疫調(diào)節(jié)中扮演著重要角色，其表達(dá)和活性的調(diào)節(jié)對(duì)于理解炎癥的發(fā)生發(fā)展以及發(fā)現(xiàn)新的抗炎藥物具有重要意義。
熱銷產(chǎn)品
Recombinant Human Interleukin-8 (CXCL8), partial (Active) (CSB-YP011671HU1)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human CXCL8 at 2 μg/ml can bind Anti-CXCL8 recombinant antibody (CSB-RA011671MA1HU). The EC50 is 43.95-46.76 ng/mL.
IL8 Recombinant Monoclonal Antibody (CSB-RA582227A0HU)
驗(yàn)證數(shù)據(jù)
Overlay Peak curve showing U937 cells stained with CSB-RA582227A0HU (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1μg/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4℃.Control antibody (green line) was rabbit IgG (1μg/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
Human Interleukin 8,IL-8 ELISA KIT (CSB-E04641h)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-E04641h
規(guī)格：96T/48T
靈敏度：7.110 pg/mL
檢測(cè)范圍：31.25 pg/mL-2000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
CXCL8 Antibodies
CXCL8 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA08327C0Rb | CXCL8 Antibody, FITC conjugated | Human | |
| CSB-PA08327D0Rb | CXCL8 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA011671GA01HU | CXCL8 Antibody | Human | ELISA,IHC |
| CSB-PA08327A0Rb | CXCL8 Antibody | Human | ELISA, WB, IHC |
| CSB-MA083271A0m | CXCL8 Monoclonal Antibody | Human | ELISA,IHC |
| CSB-PA003036 | CXCL8 Antibody | Human | WB, IHC, ELISA |
| CSB-PA004977 | CXCL8 Antibody | Human | WB, ELISA |
| CSB-PA009564 | CXCL8 Antibody | Human | IHC, ELISA |
| CSB-PA08329A0Rb | CXCL8 Antibody | Human | ELISA, IF |
| CSB-PA08329D0Rb | CXCL8 Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA582227A0HU | IL8 Recombinant Monoclonal Antibody | Human | ELISA, FC |
CXCL8 for Gallus gallus
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA15789B0Rb | CXCL8 Antibody, HRP conjugated | Gallus gallus | ELISA |
| CSB-PA15789A0Rb | CXCL8 Antibody | Gallus gallus | ELISA |
CXCL8 for Dog
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA011671YA01DO | CXCL8 Antibody | Dog | ELISA |
CXCL8 Proteins
CXCL8 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011671BO CSB-BP011671BO CSB-MP011671BO CSB-EP011671BO-B |
Recombinant Bovine Interleukin-8 (IL8) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCL8 Proteins for Macaca mulatta (Rhesus macaque)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011671MOW CSB-EP011671MOW CSB-BP011671MOW CSB-MP011671MOW CSB-EP011671MOW-B |
Recombinant Macaca mulatta Interleukin-8 (IL8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP003171MOW | Recombinant Rhesus Macaque Interleukin-8 protein (CXCL8) | E.Coli |
CXCL8 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011671HU | Recombinant Human Interleukin-8 (CXCL8) | Yeast |
| CSB-EP011671HU1 | Recombinant Human Interleukin-8 (CXCL8), partial | E.coli |
| CSB-AP001761HU | Recombinant Human Interleukin-8?protein (CXCL8), partial (Active) | E.Coli |
| CSB-AP001771HU | Recombinant Human Interleukin-8 (CXCL8), partial (Active) | E.Coli |
| CSB-BP011671HU CSB-MP011671HU CSB-EP011671HU-B |
Recombinant Human Interleukin-8 (CXCL8) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP004621HU | Recombinant Human Interleukin-8 (CXCL8) (Active) | E.coli |
| CSB-AP004641HU | Recombinant Human Interleukin-8 (CXCL8) (Active) | Mammalian cell |
| CSB-EP011671HU | Recombinant Human Interleukin-8 (CXCL8), partial | E.coli |
CXCL8 Proteins for Oryctolagus cuniculus (Rabbit)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011671RB CSB-EP011671RB CSB-BP011671RB CSB-MP011671RB CSB-EP011671RB-B |
Recombinant Rabbit Interleukin-8 (CXCL8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCL8 Proteins for Ovis aries (Sheep)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011671SH CSB-BP011671SH CSB-MP011671SH CSB-EP011671SH-B |
Recombinant Sheep Interleukin-8 (IL8) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP011671SH | Recombinant Sheep Interleukin-8 (IL8) | E.coli |
CXCL8 Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011671PI CSB-EP011671PI CSB-BP011671PI CSB-MP011671PI CSB-EP011671PI-B |
Recombinant Pig Interleukin-8 (IL8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCL8 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011671DO | Recombinant Dog Interleukin-8 (CXCL8) | Yeast |
| CSB-EP011671DO | Recombinant Dog Interleukin-8 (CXCL8) | E.coli |
CXCL8 Proteins for Cavia porcellus (Guinea pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011671GU CSB-EP011671GU CSB-BP011671GU CSB-MP011671GU CSB-EP011671GU-B |
Recombinant Guinea pig Interleukin-8 (IL8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCL8 Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011671CH CSB-EP011671CH CSB-BP011671CH CSB-MP011671CH CSB-EP011671CH-B |
Recombinant Chicken Interleukin-8 (IL8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP011671CH1 | Recombinant Chicken Interleukin-8 (CXCL8), partial | E.coli |
| CSB-EP011671CH1e1 | Recombinant chicken Interleukin-8 (CXCL8), partial | E.coli |
CXCL8 Proteins for Equus caballus (Horse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011671HO CSB-EP011671HO CSB-BP011671HO CSB-MP011671HO CSB-EP011671HO-B |
Recombinant Horse Interleukin-8 (IL8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCL8 Proteins for Macaca nemestrina (Pig-tailed macaque)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP302334MOX CSB-EP302334MOX CSB-BP302334MOX CSB-MP302334MOX CSB-EP302334MOX-B |
Recombinant Macaca nemestrina Interleukin-8 (IL8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCL8 Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP342421DRI CSB-EP342421DRI CSB-BP342421DRI CSB-MP342421DRI CSB-EP342421DRI-B |
Recombinant Cercocebus atys Interleukin-8 (IL8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCL8 Proteins for Dasypus novemcinctus (Nine-banded armadillo)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP604585DIO CSB-EP604585DIO CSB-BP604585DIO CSB-MP604585DIO CSB-EP604585DIO-B |
Recombinant Dasypus novemcinctus Interleukin-8 (IL8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCL8 Proteins for Tursiops truncatus (Atlantic bottle-nosed dolphin) (Delphinus truncatus)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP767171TRF CSB-EP767171TRF CSB-BP767171TRF CSB-MP767171TRF CSB-EP767171TRF-B |
Recombinant Tursiops truncatus Interleukin-8 (IL8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCL8 Proteins for Felis catus (Cat) (Felis silvestris catus)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP896429CA CSB-EP896429CA CSB-BP896429CA CSB-MP896429CA CSB-EP896429CA-B |
Recombinant Cat Interleukin-8 (IL8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CXCL8 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-MP011671DO CSB-EP011671DO-B |
Recombinant Dog Interleukin-8 (CXCL8) | Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-BP011671DO CSB-EP011671DO-B |
Recombinant Dog Interleukin-8 (CXCL8) | Baculovirus In Vivo Biotinylation in E.coli |
CXCL8 ELISA Kit
CXCL8 ELISA Kit for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E13052B | Bovine Interleukin 8,IL-8 ELISA Kit | serum, plasma, tissue homogenates | 50 pg/mL |
CXCL8 ELISA Kit for Gallus gallus (Chicken)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E14191C | Chicken Interleukin 8(IL-8) ELISA Kit | serum, plasma, tissue homogenates | 0.78 pg/mL |
CXCL8 ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08052c | Dog Interleukin-8,IL-8 ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 0.146 ng/mL |
CXCL8 ELISA Kit for Guinea Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E13096Gp | Guinea pig Interleukin 8,IL-8 ELISA Kit | serum, plasma, tissue homogenates | 7.8 pg/mL |
CXCL8 ELISA Kit for Equus caballus (Horse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E14021Hs | Horse Interleukin 8,IL-8 ELISA Kit | serum, plasma, tissue homogenates | 3.9 pg/mL |
CXCL8 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04641h | Human Interleukin 8,IL-8 ELISA KIT | serum, cell culture supernates, saliva, urine, cerebrospinal fluid (CSF), tissue homogenates, cell lysates | 7.110 pg/mL |
CXCL8 ELISA Kit for Monkey
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08051Mo | Monkey Interleukin-8,IL-8 ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 7.81 pg/mL |
CXCL8 ELISA Kit for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E06787p | Pig interleukin 8,IL-8 ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 31.25 pg/mL |
CXCL8 ELISA Kit for Oryctolagus cuniculus (Rabbit)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E06905Rb | Rabbit Interleukin 8,IL-8 ELISA Kit | serum, plasma, tissue homogenates | 5.8 pg/mL |
CXCL8 ELISA Kit for Ovis aries (Sheep)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E13202Sh | Sheep Interleukin-8,IL-8 ELISA Kit | serum, plasma, tissue homogenates | 1.56 pg/mL |
