MSTN
MSTN，即肌生長抑制素，是一種在哺乳動物肌肉骨骼系統中起關鍵調控作用的分泌性蛋白，屬于TGF-β超家族成員。其結構包括N-末端的分泌信號肽和半胱氨酸結構。MSTN通過與其受體結合，抑制肌肉細胞的生長、分化和增殖，從而調控肌肉的發育。在信號轉導過程中，MSTN與胞質內受體形成復合物，進而激活Smads蛋白，使其磷酸化并進入細胞核調節靶基因表達。此外，MSTN還涉及MAPK和p38等信號通路的轉導，對肌肉細胞增殖周期產生影響。MSTN的復雜結構和功能使其在生物學和醫學領域具有廣泛的應用前景，尤其在肌肉生長調控、疾病治療及肉化劑開發等方面。
熱銷產品
Recombinant Human Growth/differentiation factor 8 (MSTN) (Active) (CSB-MP015057HU(A4))
驗證數據
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(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Activity
Measured by its binding ability in a functional ELISA. Immobilized Human MSTN(GDF-8) at 2 μg/ml can bind Human ACVR2B (CSB-MP623829HUi9). The EC50 is 68.26-74.59 ng/mL.
MSTN Antibody (CSB-PA11869A0Rb)
驗證數據
Western Blot
Positive WB detected in: 293T whole cell lysate, Hela whole cell lysate, U251 whole cell lysate
All lanes: MSTN antibody at 4µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 43 kDa
Observed band size: 43 kDa
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA11869A0Rb at dilution of 1:100
Human Myostatin,MSTN ELISA Kit (CSB-E11300h)
驗證數據
貨號：CSB-E11300h
規格：96T/48T
靈敏度：0.312 ng/mL
檢測范圍：0.625 ng/mL-20 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
MSTN Antibodies
MSTN for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA015057GA01HU | MSTN Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA11869A0Rb | MSTN Antibody | Human | ELISA, WB, IHC |
| CSB-PA11869B0Rb | MSTN Antibody, HRP conjugated | Human | ELISA |
| CSB-PA008776 | MSTN Antibody | Human,Mouse | IHC, ELISA |
| CSB-PA293957 | MSTN Antibody | Human,Mouse,Rat | ELISA,IHC |
MSTN Proteins
MSTN Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP015057HU CSB-BP015057HU CSB-EP015057HU-B |
Recombinant Human Growth/differentiation factor 8 (MSTN) | Yeast Baculovirus In Vivo Biotinylation in E.coli |
| CSB-EP015057HU | Recombinant Human Growth/differentiation factor 8 (MSTN) | E.coli |
| CSB-MP015057HU(A4) | Recombinant Human Growth/differentiation factor 8 (MSTN) (Active) | Mammalian cell |
| CSB-EP015057HUd7 | Recombinant Human Growth/differentiation factor 8 (MSTN) | E.coli |
MSTN ELISA Kit
MSTN ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E11300h | Human Myostatin,MSTN ELISA Kit | serum, plasma, tissue homogenates | 0.312 ng/mL |
