Recombinant Schizosaccharomyces pombe Glucose-repressible alcohol dehydrogenase transcriptional effector (ccr4), partial

中文名稱：

Recombinant Schizosaccharomyces pombe Glucose-repressible alcohol dehydrogenase transcriptional effector(ccr4) ,partial
貨號：

CSB-YP527967SXV
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Schizosaccharomyces pombe Glucose-repressible alcohol dehydrogenase transcriptional effector(ccr4) ,partial
貨號：

CSB-EP527967SXV
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Schizosaccharomyces pombe Glucose-repressible alcohol dehydrogenase transcriptional effector(ccr4) ,partial
貨號：

CSB-EP527967SXV-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Schizosaccharomyces pombe Glucose-repressible alcohol dehydrogenase transcriptional effector(ccr4) ,partial
貨號：

CSB-BP527967SXV
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Schizosaccharomyces pombe Glucose-repressible alcohol dehydrogenase transcriptional effector(ccr4) ,partial
貨號：

CSB-MP527967SXV
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

ccr4
Uniprot No.：

O74874
別名：

ccr4; SPCC31H12.08c; SPCC5E4.02cGlucose-repressible alcohol dehydrogenase transcriptional effector; EC 3.1.13.4; Carbon catabolite repressor protein 4; Cytoplasmic deadenylase
種屬：

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA. Participates in the shortening of poly(A)-tails. Erh1-mmi1 complex-mediated recruitment of CCR4-NOT to target RNAs promotes heterochromatin formation at RNAi-dependent heterochromatin domains (HOODs), including a subset of meiotic genes, lncRNAs and retrotransposons. Recruitment of the CCR4-NOT complex to rDNA promotes rDNA heterochromatin assembly.
基因功能參考文獻(xiàn)：
1. The molecular architecture of the CCR4-NOT complex suggests that the nuclease module is located near the S. pombe-specific subunit Mmi1. PMID: 26804377
亞細(xì)胞定位：

Cytoplasm. Nucleus.
蛋白家族：

CCR4/nocturin family
數(shù)據(jù)庫鏈接：

KEGG: spo:SPCC31H12.08c

STRING: 4896.SPCC31H12.08c.1