Recombinant Rat LIM domain-containing protein 1 (Limd1)

中文名稱：

大鼠Limd1重組蛋白
貨號(hào)：

CSB-YP012949RA
規(guī)格：
來源：

Yeast
其他：

中文名稱：

大鼠Limd1重組蛋白
貨號(hào)：

CSB-EP012949RA
規(guī)格：
來源：

E.coli
其他：

中文名稱：

大鼠Limd1重組蛋白
貨號(hào)：

CSB-EP012949RA-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Limd1重組蛋白
貨號(hào)：

CSB-BP012949RA
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Limd1重組蛋白
貨號(hào)：

CSB-MP012949RA
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Limd1
Uniprot No.：

B5DEH0
別名：

Limd1LIM domain-containing protein 1
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達(dá)區(qū)域：

1-663
氨基酸序列

MDKYDDLGLE ASKFIEDLNM YEASKDGLFR VDKGASNNPE FEETRRVFAT KMAKIHLQQQ QQQQLLQEEA LPRAGRSPIN GGNRQGVSSK LAADGAAKPP LAVPTVAPGL ATTTMAVQSS YPPQEQRTRP SAHGARPGSQ NCGSREGPVS SQRPALHGLG PCEDPSCLTH GDYYDNFSLA SPQWGDKPEE SPSMSLSVGS GWPGCPGNDS LSHRSCGDSH PYHPQLSMCS GRSFESGQDS GIGGHSSEKP TGLWSTASSQ RVNLGFSSTG LENGTPAQPK GTTVSAPMVP SSTSQGACLR RDSSLGYEAP GRVFKPLVDT QPWLQDGPKS YLSVSAPLSS TTSKDNAQTG MTAGLDPKLG CVESGTSPKP SPTSNVHPVM SAPSELSCKE SPPSWSTDSS LGPVLPESPT PSRVRLPCQT LTPGPELGPS TAELKLEALT QRLEREMDAH PKADYFGACV KCSKGVFGAG QACQAMGDLY HDACFTCAAC SRKLRGKAFY FVNGKVFCEE DFLYSGFQQS ADRCFLCGHL IMDMILQALG KSYHPGCFRC VICNECLDGV PFTVDSENKI YCVRDYHKVL APKCAACGLP ILPPEGSDET IRVVSMDRDY HVECYHCEDC GLELNDEDGH RCYPLEDHLF CHSCHVKRLE KGPSPASLHQ HHF
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing and is essential for P-body formation and integrity. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. Acts as a transcriptional corepressor for SNAI1- and SNAI2/SLUG-dependent repression of E-cadherin transcription. Negatively regulates the Hippo signaling pathway and antagonizes phosphorylation of YAP1. Inhibits E2F-mediated transcription, and suppresses the expression of the majority of genes with E2F1-responsive elements. Regulates osteoblast development, function, differentiation and stress osteoclastogenesis. Enhances the ability of TRAF6 to activate adapter protein complex 1 (AP-1) and negatively regulates the canonical Wnt receptor signaling pathway in osteoblasts. May act as a tumor suppressor by inhibiting cell proliferation.
亞細(xì)胞定位：

Cytoplasm. Nucleus. Cytoplasm, P-body. Cell junction, adherens junction. Cell junction, focal adhesion.
蛋白家族：

Zyxin/ajuba family
數(shù)據(jù)庫鏈接：

KEGG: rno:316101

STRING: 10116.ENSRNOP00000006554

UniGene: Rn.228776