Recombinant Human Liprin-beta-2 (PPFIBP2), partial

中文名稱：

人PPFIBP2重組蛋白
貨號(hào)：

CSB-YP847688HU
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

人PPFIBP2重組蛋白
貨號(hào)：

CSB-EP847688HU
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱：

人PPFIBP2重組蛋白
貨號(hào)：

CSB-EP847688HU-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人PPFIBP2重組蛋白
貨號(hào)：

CSB-BP847688HU
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

人PPFIBP2重組蛋白
貨號(hào)：

CSB-MP847688HU
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

PPFIBP2
Uniprot No.：

Q8ND30
別名：

PPFIBP2; Liprin-beta-2; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2; PTPRF-interacting protein-binding protein 2
種屬：

Homo sapiens (Human)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.
基因功能參考文獻(xiàn)：
1. Analysis of the role of liprin-beta1 and liprin-beta2 has shown that while liprin-beta1 contributes positively to tumour cell motility in vitro; liprin-beta2 has a negative effect on both cell motility and invasion. PMID: 26663347
2. rs12791447 is associated with prostate cancer susceptibility in Asians. mRNA levels of PPFIBP2 are differentially expressed in prostate tumours and paired normal tissues. PMID: 26443449
3. Knockdown of either Rab17 or liprin-beta2 restores invasiveness of ERK2-depleted cells, indicating that ERK2 drives invasion of MDA-MB-231 cells by suppressing expression of these genes. PMID: 22328529
4. analysis of crystal structure of the central coiled-coil domain from human liprin-beta2 PMID: 21462929
蛋白家族：

Liprin family, Liprin-beta subfamily
組織特異性：

Widely expressed.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 9250

OMIM: 603142

KEGG: hsa:8495

STRING: 9606.ENSP00000299492

UniGene: Hs.655714