Western blot
All lanes: PPFIBP2 antibody at 6μg/ml + HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 99, 87, 84 kDa
Observed band size: 99 kDa
PPFIBP2 antibody; Liprin-beta-2 antibody; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2 antibody; PTPRF-interacting protein-binding protein 2 antibody
宿主:
Rabbit
反應種屬:
Human
免疫原:
Recombinant Human Liprin-beta-2 protein (101-400AA)
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.
基因功能參考文獻:
Analysis of the role of liprin-beta1 and liprin-beta2 has shown that while liprin-beta1 contributes positively to tumour cell motility in vitro; liprin-beta2 has a negative effect on both cell motility and invasion. PMID: 26663347
rs12791447 is associated with prostate cancer susceptibility in Asians. mRNA levels of PPFIBP2 are differentially expressed in prostate tumours and paired normal tissues. PMID: 26443449
Knockdown of either Rab17 or liprin-beta2 restores invasiveness of ERK2-depleted cells, indicating that ERK2 drives invasion of MDA-MB-231 cells by suppressing expression of these genes. PMID: 22328529
analysis of crystal structure of the central coiled-coil domain from human liprin-beta2 PMID: 21462929