SCN2B Antibody
-
中文名稱：SCN2B兔多克隆抗體
-
貨號：CSB-PA020838ESR1HU
-
規格：￥440
-
圖片：
-
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA020838ESR1HU at dilution of 1:100
-
-
其他：
產品詳情
-
產品名稱：Rabbit anti-Homo sapiens (Human) SCN2B Polyclonal antibody
-
Uniprot No.：
-
基因名：SCN2B
-
別名：SCN2B; UNQ326/PRO386; Sodium channel subunit beta-2
-
宿主：Rabbit
-
反應種屬：Human
-
免疫原：Recombinant Human Sodium channel subunit beta-2 protein (30-160AA)
-
免疫原種屬：Homo sapiens (Human)
-
標記方式：Non-conjugated
-
克隆類型：Polyclonal
-
抗體亞型：IgG
-
純化方式：Antigen Affinity Purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
-
產品提供形式：Liquid
-
應用范圍：ELISA, IHC
-
推薦稀釋比：
Application Recommended Dilution IHC 1:20-1:200 -
Protocols：
-
儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
-
功能：Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier.
-
基因功能參考文獻：
- Findings add to the understanding of beta2 role in Nav 1.5 trafficking and localisation, which must influence cell excitability and electrical coupling in the heart. PMID: 28597987
- The authors identified a flexible loop formed by (72)Cys and (75)Cys, a unique feature among the four beta-subunit isoforms. PMID: 26894959
- With increased beta-2 expression, prostate cancer cells display a trend of enhanced association with nerve axons. PMID: 24892658
- SCN2B is a new candidate gene associated with Brugada syndrome. PMID: 23559163
- beta2 is a PS/gamma-secretase substrate, gamma-secretase mediated cleavage of beta2-C-terminal fragment is required for cell-cell adhesion and migration of beta2-expressing cells PMID: 15833746
顯示更多
收起更多
-
相關疾病：Atrial fibrillation, familial, 14 (ATFB14)
-
亞細胞定位：Membrane; Single-pass type I membrane protein.
-
蛋白家族：Sodium channel auxiliary subunit SCN2B (TC 8.A.17) family
-
組織特異性：Brain specific.
-
數據庫鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
-
-
-
-
-
