PRKACG Antibody

說(shuō)明書(shū)

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) PRKACG Polyclonal antibody
Uniprot No.：

P22612
基因名：

PRKACG
別名：

cAMP-dependent protein kinase catalytic subunit gamma antibody; KAPCG_HUMAN antibody; KAPG antibody; PKA C gamma antibody; PKA C-gamma antibody; PKACg antibody; PRKACG antibody; Protein kinase cAMP dependent catalytic gamma antibody; Serine (threonine) protein kinase antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human cAMP-dependent protein kinase catalytic subunit gamma protein (1-43AA)
免疫原種屬：

Homo sapiens (Human)

標(biāo)記方式：

Non-conjugated

本頁(yè)面中的產(chǎn)品，PRKACG Antibody (CSB-PA018690LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于PRKACG Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

標(biāo)記方式	貨號(hào)	產(chǎn)品名稱	應(yīng)用
HRP	CSB-PA018690LB01HU	PRKACG Antibody, HRP conjugated	ELISA
FITC	CSB-PA018690LC01HU	PRKACG Antibody, FITC conjugated
Biotin	CSB-PA018690LD01HU	PRKACG Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Phosphorylates a large number of substrates in the cytoplasm and the nucleus.
基因功能參考文獻(xiàn)：
1. The missense p.74Ile>Met PRKACG mutation is associated with a marked defect in proplatelet formation and a low level in filamin A in megakaryocytes. PMID: 25061177
2. PKA-mediated phosphorylation of GPIbbeta at Ser(166) negatively regulates VWF binding to GPIb-IX and is one of the mechanisms by which PKA mediates platelet inhibition PMID: 12361948
3. Results suggest that Cgamma and Calpha differ in structure and function in vitro, supporting the hypothesis that functionally different C-subunit isozymes could affect cAMP signal transduction downstream of protein kinase A activation. PMID: 15039079
相關(guān)疾病：

Bleeding disorder, platelet-type 19 (BDPLT19)
蛋白家族：

Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily
組織特異性：

Testis specific. But important tissues such as brain and ovary have not been analyzed for the content of transcript.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 9382

OMIM: 176893

KEGG: hsa:5568

STRING: 9606.ENSP00000366488

UniGene: Hs.158029

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