PRKACG Antibody, FITC conjugated
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中文名稱：
PRKACG兔多克隆抗體, FITC偶聯
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貨號：
CSB-PA018690LC01HU
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規格：
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其他：
產品詳情
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產品名稱：
Rabbit anti-Homo sapiens (Human) PRKACG Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：
cAMP-dependent protein kinase catalytic subunit gamma antibody; KAPCG_HUMAN antibody; KAPG antibody; PKA C gamma antibody; PKA C-gamma antibody; PKACg antibody; PRKACG antibody; Protein kinase cAMP dependent catalytic gamma antibody; Serine (threonine) protein kinase antibody
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宿主：
Rabbit
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反應種屬：
Human
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免疫原：
Recombinant Human cAMP-dependent protein kinase catalytic subunit gamma protein (1-43AA)
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免疫原種屬：
Homo sapiens (Human)
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標記方式：
FITC
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克隆類型：
Polyclonal
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抗體亞型：
IgG
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純化方式：
>95%, Protein G purified
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濃度：
It differs from different batches. Please contact us to confirm it.
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保存緩沖液：
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
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產品提供形式：
Liquid
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儲存條件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶點詳情
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功能：
Phosphorylates a large number of substrates in the cytoplasm and the nucleus.
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基因功能參考文獻：
- The missense p.74Ile>Met PRKACG mutation is associated with a marked defect in proplatelet formation and a low level in filamin A in megakaryocytes. PMID: 25061177
- PKA-mediated phosphorylation of GPIbbeta at Ser(166) negatively regulates VWF binding to GPIb-IX and is one of the mechanisms by which PKA mediates platelet inhibition PMID: 12361948
- Results suggest that Cgamma and Calpha differ in structure and function in vitro, supporting the hypothesis that functionally different C-subunit isozymes could affect cAMP signal transduction downstream of protein kinase A activation. PMID: 15039079
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相關疾病：
Bleeding disorder, platelet-type 19 (BDPLT19)
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蛋白家族：
Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily
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組織特異性：
Testis specific. But important tissues such as brain and ovary have not been analyzed for the content of transcript.
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數據庫鏈接：
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