LYRM1 Antibody, FITC conjugated

說(shuō)明書(shū)

產(chǎn)品詳情

產(chǎn)品名稱(chēng)：

Rabbit anti-Homo sapiens (Human) LYRM1 Polyclonal antibody
Uniprot No.：

O43325
基因名：

LYRM1
別名：

1110065L10Rik antibody; 2310004B22Rik antibody; 4930404J24Rik antibody; A211C6.1 antibody; LYR motif containing 1 antibody; LYR motif containing protein 1 antibody; LYR motif-containing protein 1 antibody; LYRM 1 antibody; lyrm1 antibody; LYRM1_HUMAN antibody; OTTHUMP00000162292 antibody; OTTMUSP00000031126 antibody; OTTMUSP00000031127 antibody; OTTMUSP00000031128 antibody; OTTMUSP00000031129 antibody; RGD1563498 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human LYR motif-containing protein 1 protein (1-122AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

FITC
克隆類(lèi)型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May promote cell proliferation and inhibition of apoptosis of preadipocytes.
基因功能參考文獻(xiàn)：
1. alpha-LA protects 3T3-L1 adipocytes from LYRM1-induced insulin resistance partially via its capacity to restore mitochondrial function and/or increase phosphorylation of IRS-1 and Akt. PMID: 22820890
2. overexpression of LYRM1 caused mitochondrial dysfunction in adipocytes, which might be responsible for the development of LYRM1-induced insulin resistance PMID: 20826099
3. Data suggest that LYRM1 might have the potential to modulate cell growth, apoptosis, and heart development. PMID: 20938407
4. By increasing cell proliferation and lowering the rate of apoptosis, LYRM1 has the potential to modulate the size of the preadipocyte pool and influence adipose tissue homeostasis PMID: 19022914
相關(guān)疾病：

When overexpressed, may be involved in obesity-associated insulin resistance, possibly by causing mitochondrial dysfunction in adipocytes.
亞細(xì)胞定位：

Nucleus.
蛋白家族：

Complex I LYR family
組織特異性：

High levels in adipose tissue.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 25074

OMIM: 614709

KEGG: hsa:57149

STRING: 9606.ENSP00000219168

UniGene: Hs.745012

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