LYRM1 Antibody

中文名稱：

LYRM1兔多克隆抗體
貨號：

CSB-PA013272LA01HU
規(guī)格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA013272LA01HU at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) LYRM1 Polyclonal antibody
Uniprot No.：

O43325
基因名：

LYRM1
別名：

1110065L10Rik antibody; 2310004B22Rik antibody; 4930404J24Rik antibody; A211C6.1 antibody; LYR motif containing 1 antibody; LYR motif containing protein 1 antibody; LYR motif-containing protein 1 antibody; LYRM 1 antibody; lyrm1 antibody; LYRM1_HUMAN antibody; OTTHUMP00000162292 antibody; OTTMUSP00000031126 antibody; OTTMUSP00000031127 antibody; OTTMUSP00000031128 antibody; OTTMUSP00000031129 antibody; RGD1563498 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human LYR motif-containing protein 1 protein (1-122AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，LYRM1 Antibody (CSB-PA013272LA01HU)，的標記方式是Non-conjugated。對于LYRM1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA013272LB01HU	LYRM1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA013272LC01HU	LYRM1 Antibody, FITC conjugated
Biotin	CSB-PA013272LD01HU	LYRM1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May promote cell proliferation and inhibition of apoptosis of preadipocytes.
基因功能參考文獻：
1. alpha-LA protects 3T3-L1 adipocytes from LYRM1-induced insulin resistance partially via its capacity to restore mitochondrial function and/or increase phosphorylation of IRS-1 and Akt. PMID: 22820890
2. overexpression of LYRM1 caused mitochondrial dysfunction in adipocytes, which might be responsible for the development of LYRM1-induced insulin resistance PMID: 20826099
3. Data suggest that LYRM1 might have the potential to modulate cell growth, apoptosis, and heart development. PMID: 20938407
4. By increasing cell proliferation and lowering the rate of apoptosis, LYRM1 has the potential to modulate the size of the preadipocyte pool and influence adipose tissue homeostasis PMID: 19022914
相關疾病：

When overexpressed, may be involved in obesity-associated insulin resistance, possibly by causing mitochondrial dysfunction in adipocytes.
亞細胞定位：

Nucleus.
蛋白家族：

Complex I LYR family
組織特異性：

High levels in adipose tissue.
數據庫鏈接：

HGNC: 25074

OMIM: 614709

KEGG: hsa:57149

STRING: 9606.ENSP00000219168

UniGene: Hs.745012

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