INHBA
INHBA蛋白全名為抑制素β亞基A（inhibin beta A），常見(jiàn)別名包括激活素βA亞基（inhibin βA）和FSH釋放蛋白。該蛋白屬于轉(zhuǎn)化生長(zhǎng)因子-β超家族，參與活化素和抑制素蛋白復(fù)合物的形成，在性腺和垂體中發(fā)揮相反的功能。INHBA可以與其他亞基結(jié)合形成二聚體，調(diào)節(jié)促卵泡激素的合成，對(duì)生殖和內(nèi)分泌系統(tǒng)具有重要影響。研究表明，INHBA在多種癌癥中存在罕見(jiàn)突變和過(guò)表達(dá)現(xiàn)象，但在許多癌癥中表現(xiàn)出抗腫瘤作用，通過(guò)誘導(dǎo)生長(zhǎng)抑制和凋亡來(lái)抑制腫瘤進(jìn)展。此外，INHBA與骨骼疾病、惡性腫瘤和惡病質(zhì)等疾病相關(guān)，成為潛在的治療靶點(diǎn)。目前，針對(duì)INHBA的藥物研發(fā)主要集中在激活素A和抑制素的靶向治療，相關(guān)抗體藥物和臨床試驗(yàn)也在積極進(jìn)行中，為疾病治療提供了新的思路。
熱銷產(chǎn)品
Recombinant Human Inhibin beta A chain (INHBA) (Active) (CSB-MP011719HU-WD)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
INHBA Antibody (CSB-PA07589A0Rb)
驗(yàn)證數(shù)據(jù)
Western blot
All lanes: INHBA antibody at 2µg/ml
Lane 1: Hela whole cell lysate
Lane 2: HepG2 whole cell lysate
Lane 3: A549 whole cell lysate
Lane 4: MCF-7 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 48 kDa
Observed band size: 48 kDa
Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA07589A0Rb at dilution of 1:100
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA07589A0Rb at dilution of 1:100
INHBA Antibodies
INHBA for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA011719GA01HU | INHBA Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA07589A0Rb | INHBA Antibody | Human | ELISA, WB, IHC |
| CSB-PA07589B0Rb | INHBA Antibody, HRP conjugated | Human | ELISA |
| CSB-PA07589C0Rb | INHBA Antibody, FITC conjugated | Human | |
| CSB-PA07589D0Rb | INHBA Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA005668 | INHBA Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA903855 | INHBA Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA055706 | INHBA Antibody | Human,Mouse,Rat | ELISA,WB |
INHBA Proteins
INHBA Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011719RA CSB-EP011719RA CSB-BP011719RA CSB-MP011719RA CSB-EP011719RA-B |
Recombinant Rat Inhibin beta A chain (Inhba) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
INHBA Proteins for Ovis aries (Sheep)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011719SH CSB-EP011719SH CSB-BP011719SH CSB-MP011719SH CSB-EP011719SH-B |
Recombinant Sheep Inhibin beta A chain (INHBA) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
INHBA Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011719CH CSB-EP011719CH CSB-BP011719CH CSB-MP011719CH CSB-EP011719CH-B |
Recombinant Chicken Inhibin beta A chain (INHBA) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
INHBA Proteins for Equus caballus (Horse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011719HO CSB-EP011719HO CSB-BP011719HO CSB-MP011719HO CSB-EP011719HO-B |
Recombinant Horse Inhibin beta A chain (INHBA) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
INHBA Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011719PI CSB-EP011719PI CSB-BP011719PI CSB-MP011719PI CSB-EP011719PI-B |
Recombinant Pig Inhibin beta A chain (INHBA) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
INHBA Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011719BO CSB-EP011719BO CSB-BP011719BO CSB-MP011719BO CSB-EP011719BO-B |
Recombinant Bovine Inhibin beta A chain (INHBA) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
INHBA Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP011719HU CSB-MP011719HU CSB-EP011719HU-B |
Recombinant Human Inhibin beta A chain (INHBA) | Yeast Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP011719HU | Recombinant Human Inhibin beta A chain (INHBA) | E.coli |
| CSB-AP004011HU | Recombinant Human Inhibin beta A chain (INHBA) (Active) | Mammalian cell |
| CSB-BP011719HU | Recombinant Human Inhibin beta A chain (INHBA) | Baculovirus |
| CSB-MP011719HU-WD | Recombinant Human Inhibin beta A chain (INHBA) (Active) | Mammalian cell |
| CSB-EP011719HUc7 | Recombinant Human Inhibin beta A chain (INHBA) | E.coli |
| CSB-MP011719HU1 | Recombinant Human Inhibin beta A chain (INHBA) | Mammalian cell |
| CSB-MP011719HU1b0 | Recombinant Human Inhibin beta A chain (INHBA) (Active) | Mammalian cell |
INHBA Proteins for Felis catus (Cat) (Felis silvestris catus)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP751056CA CSB-EP751056CA CSB-BP751056CA CSB-MP751056CA CSB-EP751056CA-B |
Recombinant Cat Inhibin beta A chain (INHBA) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
INHBA ELISA Kit
INHBA ELISA Kit for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL011719BO | Bovine Inhibin beta A chain(INHBA) ELISA kit | serum, plasma, tissue homogenates | 15 pg/mL |
