EGLN3
Egl nine homolog 3 is a protein in humans that is encoded by EGLN3 gene. Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF2A. Hydroxylation on the NODD site by EGLN3 appears to require prior hydroxylation on the CODD site. Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
EGLN3 Antibodies
EGLN3 for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA14797A0Rb | Egln3 Antibody | Mouse, Rat | ELISA, WB |
EGLN3 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA007483GA01HU | EGLN3 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA880987ESR2HU | EGLN3 Antibody | Human | ELISA, IHC |
| CSB-PA040512 | EGLN3 Antibody | Human,Mouse,Rat | ELISA,IHC |
EGLN3 Proteins
EGLN3 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP733831RA CSB-EP733831RA CSB-BP733831RA CSB-MP733831RA CSB-EP733831RA-B |
Recombinant Rat Egl nine homolog 3 (Egln3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
EGLN3 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP849640MO CSB-EP849640MO CSB-BP849640MO CSB-MP849640MO CSB-EP849640MO-B |
Recombinant Mouse Egl nine homolog 3 (Egln3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-RP147974m | Recombinant Mouse Egl nine homolog 3 protein (Egln3) | E.coli |
EGLN3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP880987HU CSB-BP880987HU CSB-MP880987HU CSB-EP880987HU-B |
Recombinant Human Egl nine homolog 3 (EGLN3) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP880987HU | Recombinant Human Egl nine homolog 3 (EGLN3) | E.coli |
| CSB-EP880987HUb1 | Recombinant Human Egl nine homolog 3 (EGLN3) | E.coli |
