Recombinant Xenopus laevis Protein Wnt-11 (wnt11)

中文名稱：

有爪蟾蜍wnt11重組蛋白
貨號：

CSB-YP724154XBE
規格：
來源：

Yeast
其他：

中文名稱：

有爪蟾蜍wnt11重組蛋白
貨號：

CSB-EP724154XBE
規格：
來源：

E.coli
其他：

中文名稱：

有爪蟾蜍wnt11重組蛋白
貨號：

CSB-EP724154XBE-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

有爪蟾蜍wnt11重組蛋白
貨號：

CSB-BP724154XBE
規格：
來源：

Baculovirus
其他：

中文名稱：

有爪蟾蜍wnt11重組蛋白
貨號：

CSB-MP724154XBE
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

wnt11
Uniprot No.：

Q670P5
別名：

wnt11; wnt11rProtein Wnt-11; Protein Wnt-11-related; Wnt11-R; Wnt11r
種屬：

Xenopus laevis (African clawed frog)
蛋白長度：

Full Length of Mature Protein
表達區域：

23-352
氨基酸序列

IKWLALSK TPLSLPLNQT QHCKQLEGLV SSQMQLCRSN LELMQTIIHA AKEVKKTCVK AFTDMRWNCS SIELAPTFHQ DLERGTRESA FVHALSAAAI SHTIARACTT GDIPGCSCAP IPGESPGPGY RWGGCADNLN YGILMGSKFS DAPMKMKKSG SQANKLMHLH NSEVGRQVLK ASLEMKCKCH GVSGSCSIKT CWRGLQELRE IALDLKTKYL SATKVVHRPM GTRKHLVPKD IDIRPVQETE LIYLQSSPDY CLKNEKIGSH GTHERQCNKT SNGSDSCDLM CCGRGYNPYM DKVVERCLCK YHWCCYVTCK KCERTVERYV CK
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Ligand for members of the frizzled family of seven transmembrane receptors. Shares much functionality with wnt11b. Signals through a non-canonical Wnt pathway to activate Jun-N-terminal kinase (JNK) to regulate gastrulation movements. Acts in a non-cell-autonomous manner to control neural crest migration, probably acting as an extracellular signal from surrounding tissue, but is not required for neural crest induction. Acts redundantly with wnt11b during pronephros induction. Regulates cardiac morphogenesis through the activation of JNK, but is not required for cardiac differentiation. Essential for dorsal fin development; required for an epithelial to mesenchymal transformation event prior to migration of cells into the fin, and ultimately for maintenance of fin structure. Mediates dorsal fin development through a non-canonical pathway mediated by Ca(2+).
基因功能參考文獻：
1. Xenopus Wnt11-R is expressed in neural tissue, the brachial arches, and the muscle layer of the heart. PMID: 15708567
2. Wnt11-R signaling regulates a calcium sensitive EMT event essential for dorsal fin development of Xenopus. PMID: 17240368
3. wnt11r is required in a non-cell-autonomous manner to control neural crest migration. PMID: 18942153
亞細胞定位：

Secreted, extracellular space, extracellular matrix.
蛋白家族：

Wnt family
組織特異性：

In embryos, expressed in the neural tube, dorsal somite, mesenchymal cells within the dorsal fin, branchial arches and heart muscle, becoming expressed throughout the myocardium by the tadpole stage (stage 45). Prior to neural crest cell migration, expres
數據庫鏈接：

KEGG: xla:446915

UniGene: Xl.13686