Recombinant Rat Disks large-associated protein 1 (Dlgap1), partial

中文名稱：

大鼠Dlgap1重組蛋白
貨號：

CSB-YP006940RA
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Dlgap1重組蛋白
貨號：

CSB-EP006940RA
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Dlgap1重組蛋白
貨號：

CSB-EP006940RA-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Dlgap1重組蛋白
貨號：

CSB-BP006940RA
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Dlgap1重組蛋白
貨號：

CSB-MP006940RA
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Dlgap1
Uniprot No.：

P97836
別名：

Dlgap1; GkapDisks large-associated protein 1; DAP-1; Guanylate kinase-associated protein; rGKAP; PSD-95/SAP90-binding protein 1; SAP90/PSD-95-associated protein 1; SAPAP1
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Part of the postsynaptic scaffold in neuronal cells.
基因功能參考文獻：
1. Upon depolarization with high K+, neither the intensity nor distribution of label for GKAP changed, but labeling intensity for Shank at the postsynaptic density increased to ~150% of controls. PMID: 25775468
2. The C-terminal helical domain of GKAP from Rattus norvegicus was purified and crystallized as a fusion protein. PMID: 25005096
3. Phosphorylated serine residues in several of the identified phosphorylation sites were followed by prolines, suggesting prominent involvement of proline directed kinases in the regulation of PSD components. PMID: 15358237
4. Activity-dependent turnover of postsynnaptic density proteins orchestrated by GKAP is critical for homeostatic plasticity. PMID: 23143515
5. postsynaptic scaffold GKAP is degraded and dendritic spine morphology is regulated by the TRIM3 ubiquitin ligase in rat hippocampal neurons PMID: 20352094
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亞細胞定位：

Cell membrane; Peripheral membrane protein. Cell junction, synapse, postsynaptic density. Cell junction, synapse.
蛋白家族：

SAPAP family
組織特異性：

Expressed in brain and testis.
數據庫鏈接：

KEGG: rno:65040

STRING: 10116.ENSRNOP00000022351

UniGene: Rn.214229