Recombinant Rat Coiled-coil domain-containing protein 22 (Ccdc22)

中文名稱：

Recombinant Rat Coiled-coil domain-containing protein 22(Ccdc22)
貨號：

CSB-YP004681RA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Rat Coiled-coil domain-containing protein 22(Ccdc22)
貨號：

CSB-EP004681RA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Rat Coiled-coil domain-containing protein 22(Ccdc22)
貨號：

CSB-EP004681RA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Rat Coiled-coil domain-containing protein 22(Ccdc22)
貨號：

CSB-BP004681RA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Rat Coiled-coil domain-containing protein 22(Ccdc22)
貨號：

CSB-MP004681RA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Ccdc22
Uniprot No.：

P86182
別名：

Ccdc22Coiled-coil domain-containing protein 22
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full length protein
表達區域：

1-627
氨基酸序列

MEEADRILIH SLRQAGTAVP PEVQTLRAFT TELVVEAVVR CLRVINPDVG SGLSHLLPPA MSARFRLAMS LAQACMDLGY PLELGYQNFL YPSEPDLRDL LLFLAERLPT DASEDADQPA GDSAIFLRAI GSQIRDQLAL PWVPPLLRTP KVQRLQGSAL QQAFHSSRLV LPELNCRGEP REFQASPLLL PAPSQVPQLL GRAASLLEHH AIQLCQHVNR DCPGDEDRVR WASRLPSQED PRAPQQRLHK QLIEHLRQSW GPLGAPTQVR DLGEMLQAWG AKAMTGVPKG SRFTHSEKFT FHLEPQVQAA QVADIPAASQ RPEQDTRAAQ EEELESLREQ LASVNHNIEE VEANMKSLGM NLVQVETECR QSELSVAEQE QALRLKSRTV ELLPDGAANL TKLQLVVESS AQRLIHLASQ WEKHRVPLLA EYRHLRKLQD CRELESSRRL VEIQELHQSV RAAAEEARRK EEVYKQLVSE LETLPKDVSR LAYTQRILEI VGNIRKQKEE ITKILSDTKE LQKEINSLSG KLDRTFAVTD ELVFKDAKKD DAVRKAYKYL AALHENCSQL IQTIEDTGTI MREVRDLEEQ IETEMGKKTL SNLEKICEDY RALRQENAGL LGRVREV
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved in regulation of NF-kappa-B signaling. Promotes ubiquitination of I-kappa-B-kinase subunit IKBKB and its subsequent proteasomal degradation leading to NF-kappa-B activation; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. May down-regulate NF-kappa-B activity via association with COMMD1 and involving a CUL2-dependent E3 ubiquitin ligase complex. Regulates the cellular localization of COMM domain-containing proteins, such as COMMD1 and COMMD10. Component of the CCC complex, which is involved in the regulation of endosomal recycling of surface proteins, including integrins, signaling receptor and channels. The CCC complex associates with SNX17, retriever and WASH complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGA5:ITGB1. Plays a role in copper ion homeostasis. Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes.
亞細胞定位：

Endosome.
蛋白家族：

CCDC22 family
數據庫鏈接：

KEGG: rno:317381

STRING: 10116.ENSRNOP00000015547

UniGene: Rn.38478