1. Knockdown of SIRT7 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly via activation of the Wnt/beta-catenin signaling pathway. PMID: 28880264
2. HIV and drug abuse mediate astrocyte senescence in a beta-catenin-dependent manner leading to neuronal toxicity. PMID: 28612507
3. Activation of Wnt/beta-catenin signaling is required for TGF-beta/Smad2/Smad3 signaling during myofibroblast proliferation. PMID: 28244647
4. Axud1 mediated stress-induced cardiomyocytes apoptosis through activating Wnt/beta-catenin signaling pathway. PMID: 28830684
5. Postsynaptic Y654-dephosphorylation of betaCat is able to initiate retrograde signaling via Ncad-mediated transsynaptic adhesion to modulate presynaptic vesicle dynamics. PMID: 27328456
6. results suggest that activation Wnt3alpha/beta-catenin signal attenuate apoptosis of brain microvascular endothelial cells induced by ischemia PMID: 28347817
7. Identified several transcription factorss with potential binding sites in the Aqp2 gene promoter that could interact with beta-catenin in the regulation of Aqp2 gene transcription. PMID: 28298358
8. The Beta-catenin/Wnt signaling pathway mediated transcription related to neuronal structure and activity in the hippocampus. PMID: 28116168
9. Low Ctnnb1 expression is associated with hepatic fibrosis. PMID: 28177765
10. MiR-9-5p promotes MSC migration by activating beta-catenin signaling pathway. PMID: 28424168
11. uniaxial mechanical stretch could stimulate osteogenic differentiation and proliferation of BMSCs by activating the Wnt/beta-catenin signaling. PMID: 27922964
12. The cardiomyocytes were transfected with porcine cytomegalovirus (pCMV)-b-catenin plasmid in order to overexpress b-catenin. PMID: 27734460
13. Our study provides evidence that mild hypothermia reactivates the Wnt/beta-catenin signaling pathway, which is suppressed by OGD/R injury, in hippocampal neurons and protects neurons from OGD/R-induced apoptosis via the reactivation of the Wnt/beta-catenin signaling pathway, ultimately suggesting that mild hypothermia could have therapeutic effects on OGD/R-induced apoptosis. PMID: 28365156
14. Our results indicate that the Wnt signaling is activated during adipose-derived stem cells differentiation into islet b-cells, but there was no obvious enrichment of nonphosphorylated b-catenin protein. PMID: 28303247
15. These results indicated that aluminum trichloride impaired femora by inhibiting the Wnt/beta-catenin signaling pathway in young growing rats. PMID: 26474975
16. A role of beta-catenin signaling during antidiuresis and its interaction with soluble prorenin receptor and liver X receptor PMID: 26984496
17. detected a marked increase in the localization of beta-catenin in the nucleus of crypt epithelial cells in the ileum of PKD1 PMID: 26739494
18. p300 phosphorylation at Ser-89 enhances p300/beta-catenin interaction, concurrent with alveolar epithelial cell differentiation. PMID: 26833564
19. activation of the Wnt/beta-catenin signaling cascade attenuates ALD progression. PMID: 25724365
20. Wnt7b/beta-catenin signaling may play an important role infetal rat alveolar epithelial type II cells (fAEC2) transdifferentiation. PMID: 26429533
21. In this study we provided evidence that beta-catenin-dependent signaling pathway participates in the renal fibrosis induced in 2K1C rats. PMID: 25945342
22. These results suggest that beta-catenin is an important player in high phosphorus level-induced aortic calcification in chronic kidney disease. PMID: 25634106
23. GSK3beta promotes the differentiation of oligodendrocyte precursor cells via beta-catenin-mediated transcriptional regulation PMID: 24691545
24. this study provides the evidence that inhibition of nuclear translocation of beta-CATENIN enhances conversion of mouse EpiSCs to naive-like PSCs (rESCs). PMID: 25556568
25. The promotion of Beta-catenin nuclear translocation mediated by frizzled-4 receptor activation protects blood brain barrier after subarachnoid hemorrhage. PMID: 25550365
26. Early articular cartilage degeneration in a developmental dislocation of the hip model results from activation of beta-catenin. PMID: 24817933
27. beta-catenin is overexpressed in hepatic fibrosis and blockage of Wnt/beta-catenin signaling inhibits hepatic stellate cell activation. PMID: 24691643
28. Beta-catenin plays a not yet described role in thyroid function including a functional interaction with Pax8. PMID: 24645679
29. beta-catenin can enhance the odontoblastic differentiation of dental pulp cells through activation of Runx2. PMID: 24520423
30. When the Wnt/beta-catenin pathway was activated by LiCl, the expression of RANKL was significantly increased. PMID: 23271279
31. Stimulation of beta-catenin signaling induces regeneration in selected cases of hepatic insufficiency. PMID: 24122933
32. Hypdercholesterolemia in Wistar rats promoted, in addition to higher body weight gain and increased serum LDL cholesterol levels, overexpression of beta- and gamma-catenin in the detrusor muscle cells. PMID: 24139451
33. Morin by downregulating the expressions of GSK-3beta, beta-catenin and cyclin D1 ameliorated hepatic stellate cell proliferation in liver fibrosis. PMID: 24657339
34. beta-catenin signaling as a molecular rheostat in rat embryonic stem cells, regulating self-renewal. PMID: 23843312
35. Nuclear translocation of beta-catenin might play important roles in regulating signal transduction in the decompensated hypertrophy stage in hypertensive rats. PMID: 23591738
36. Piper betle may act as a potential chemopreventive agent in the early stage of colon carcinogenesis by suppressing the expressions of beta-catenin and KRAS. PMID: 24617038
37. Suggest that fluoride promotes osteoblastic differentiation through Akt- and GSK-3beta-dependent activation of Wnt/beta-catenin signaling pathway in primary rat osteoblasts. PMID: 24300170
38. the canonical Wnt/beta-catenin signaling pathway may play an important role in TCDD-induced neurotoxicity and neuronal apoptosis. PMID: 23619006
39. StarD7 and beta-catenin both regulate the effect of Annexin 5 in testosterone production of rat Leydig cells. PMID: 22898837
40. Wnt/beta-catenin signaling could induce mesenchymal stem cells aging through promoting the intracellular production of ROS, and ROS may be the main mediators of MSC aging induced by excessive activation of Wnt/beta-catenin signaling. PMID: 23124852
41. Results support LGR-5 as a putative neoplastic stem cell marker in colonic tumors co-expressing nuclear beta-catenin. PMID: 23374535
42. The results of this study suggested that axonal translation of beta-catenin plays an essential role in synapse formation. PMID: 23536073
43. Transcriptional activity of beta-catenin is necessary for the proper excitability of thalamic neurons. PMID: 23157480
44. found a glucose-dependent increase in levels of beta-catenin in the cytoplasm and nucleus of INS-1E cells. Expression of cyclin D1 also increased with glucose and required the presence of beta-catenin. PMID: 23198873
45. Beta-catenin could play an important role in bone sclerosis of subchronic fluoride exposure. PMID: 21695899
46. Wnt2 overexpression in DC3 granulosa cells promotes cytosolic and nuclear accumulation of beta-catenin (CTNNB1), but does not stimulate CTNNB1/TCF-dependent (pGL3-OT) transcriptional activity PMID: 22517624
47. Vascular cells with genetically or pharmacologically reduced TG2 activity fail to activate beta-catenin in response to warfarin. Moreover, warfarin-induced calcification is significantly reduced on the background of attenuated TG2 both in vitro and in vivo. PMID: 22034513
48. Suggest that activation of ILK activated the Wnt/beta-catenin signaling pathway in damaged podocytes in focal segmental glomerulosclerosis. PMID: 21928230
49. Subcellular trafficking of beta-catenin fosters its translocation to the nucleus via WISP1 in primary neurons during oxidant stress. PMID: 22475393
50. Tripchlorolide protects against the neurotoxicity of Abeta by regulating Wnt/beta-catenin signaling pathway. PMID: 20931782

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KEGG: rno:84353

STRING: 10116.ENSRNOP00000026016

UniGene: Rn.112601