Recombinant Protein humpback-2 (hmp-2), partial

中文名稱：

秀麗隱桿線蟲hmp-2重組蛋白
貨號：

CSB-YP528592CXY
規(guī)格：
來源：

Yeast
其他：

中文名稱：

秀麗隱桿線蟲hmp-2重組蛋白
貨號：

CSB-EP528592CXY
規(guī)格：
來源：

E.coli
其他：

中文名稱：

秀麗隱桿線蟲hmp-2重組蛋白
貨號：

CSB-EP528592CXY-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

秀麗隱桿線蟲hmp-2重組蛋白
貨號：

CSB-BP528592CXY
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

秀麗隱桿線蟲hmp-2重組蛋白
貨號：

CSB-MP528592CXY
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

hmp-2
Uniprot No.：

O44326
別名：

hmp-2; K05C4.6; Beta-catenin-like protein hmp-2; Protein humpback-2
種屬：

Caenorhabditis elegans
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

功能：

Required for cell migration during body enclosure and cell shape changes during body elongation. Plays a role in recruitment of the cadherin protein hmr-1 to adherens junctions.
基因功能參考文獻(xiàn)：
1. Deletion analysis based on the crystal structure shows that the first helix of HMP-1 is necessary for binding HMP-2 avidly in vitro and for efficient recruitment of HMP-1 to adherens junctions in embryos. HMP-2 Ser-47 and Tyr-69 flank its binding interface with HMP-1, and we show that phosphomimetic mutations at these two sites decrease binding affinity of HMP-1 to HMP-2 by 40-100-fold PMID: 28842483
2. The beta-catenin HMP-2 functions downstream of Src in parallel with the Wnt pathway in early embryogenesis of C. elegans. PMID: 21575624
亞細(xì)胞定位：

Cell junction, adherens junction.
蛋白家族：

Beta-catenin family
組織特異性：

Epidermal cells.
數(shù)據(jù)庫鏈接：

STRING: 6239.K05C4.6b

UniGene: Cel.7074