Recombinant Pig Cytochrome P450 2E1 (CYP2E1)

中文名稱：

Recombinant Pig Cytochrome P450 2E1(CYP2E1)
貨號：

CSB-YP006425PI
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Pig Cytochrome P450 2E1(CYP2E1)
貨號：

CSB-EP006425PI
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Pig Cytochrome P450 2E1(CYP2E1)
貨號：

CSB-EP006425PI-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Pig Cytochrome P450 2E1(CYP2E1)
貨號：

CSB-BP006425PI
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Pig Cytochrome P450 2E1(CYP2E1)
貨號：

CSB-MP006425PI
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

CYP2E1
Uniprot No.：

P79383
別名：

CYP2E1; CYP2ECytochrome P450 2E1; EC 1.14.14.1; 4-nitrophenol 2-hydroxylase; EC 1.14.13.n7; CYPIIE1; Cytochrome P-450-J; Cytochrome P450-J
種屬：

Sus scrofa (Pig)
蛋白長度：

Full Length of Mature Protein
表達區(qū)域：

2-495
氨基酸序列

TALGITVAL LVWLVTLLLI SIWKHIHSSW KLPPGPFPLP IVGNIFQLDL KNIPKSFTML AERYGPVFTV YLGSRRIVVL HGYKAVKEVL LHYKNEFSGR GEIPTFQVHK DKGVIFNNGP TWRDTRRFSL TTLRDFGMGK QGNEQRIQRE AHFLLEALRK THGQPFDPTF LIGCAPCNVI SDILFRQHFD YNDKTCLRLM SMFNENFYLL STGWIQLYNN FSGYLRYLPG SHRKLMKNIS EIKDYALERV KDHRDSLEPS CPRDFTDTLL MEMEKEKYSA EPIYTLDNIA VTVADMFFAG TETTSTTLRY GLLILMKYPE VEEKLHEEID RVIGPNRIPA IKDRLVMPYL DAVVHEIQRF IDLIPSNLPH EATRDTDFRD YIIPKGTVVI PTLDSVLYDS QEFPEPEKFK PEHFLNENGK FKYSDHFKAF SAGKRVCVGE GLARMELFLF MAAILQHFNL KSLVDPKDID LSPIAIGFAK IPPHYKLCVI PRSQV
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.
基因功能參考文獻：
1. A highly significant association was found between variation in skatole levels and SNPs within the CYP2E1 gene on chromosome 14. PMID: 24894739
2. The relationship between a single nucleotide polymorphism of CYP2E1 and boar taint in pork from Belgian swine is reported. PMID: 22558788
3. the G --> A substitute might be at least partially responsible for a high level of skatole in pigs PMID: 16821288
亞細胞定位：

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. Mitochondrion inner membrane; Peripheral membrane protein.
蛋白家族：

Cytochrome P450 family
數(shù)據(jù)庫鏈接：

KEGG: ssc:403216

STRING: 9823.ENSSSCP00000011493

UniGene: Ssc.15741