Recombinant Multidrug resistance protein norM (norM), partial

中文名稱：

副溶血性弧菌norM重組蛋白
貨號：

CSB-YP528111VFE
規格：
來源：

Yeast
其他：

中文名稱：

副溶血性弧菌norM重組蛋白
貨號：

CSB-EP528111VFE
規格：
來源：

E.coli
其他：

中文名稱：

副溶血性弧菌norM重組蛋白
貨號：

CSB-EP528111VFE-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

副溶血性弧菌norM重組蛋白
貨號：

CSB-BP528111VFE
規格：
來源：

Baculovirus
其他：

中文名稱：

副溶血性弧菌norM重組蛋白
貨號：

CSB-MP528111VFE
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

norM
Uniprot No.：

O82855
別名：

norM; VP1479; Multidrug resistance protein NorM; Multidrug-efflux transporter; Na(+)/drug antiporter
種屬：

Vibrio parahaemolyticus
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Multidrug efflux pump that functions as a Na(+)/drug antiporter. Confers resistance to several drugs, such as norfloxacin, ciprofloxacin, ethidium, kanamycin and streptomycin.
基因功能參考文獻：
1. In this study, we investigated the role(s) of acidic amino acid residues Asp32, Glu251, and Asp367 in the transmembrane region of NorM by site-directed mutagenesis. PMID: 15716425
2. Inactivation of norM rendered V. cholerae hypersensitive towards fluoroquinolones such as norfloxacin/ciprofloxacin. Moreover the topology of NorM was determined and amino acid residures involved in norfloxacin resistance was identified. PMID: 16954325
3. A gene (norM) for a putative multidrug efflux protein shows different substrate specificities in V. parahaemolyticus and E. coli PMID: 9661020
4. In this study, we conclude that NorM is an Na(+)-driven Na(+)/drug antiporter, which is the first example in the biological world. PMID: 11073914
亞細胞定位：

Cell inner membrane; Multi-pass membrane protein.
蛋白家族：

Multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family
數據庫鏈接：

KEGG: vpa:VP1479

STRING: 223926.VP1479