Recombinant Mouse Syntaxin-1B (Stx1b), partial

中文名稱：

小鼠Stx1b重組蛋白
貨號：

CSB-YP022896MO1
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Stx1b重組蛋白
貨號：

CSB-EP022896MO1
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Stx1b重組蛋白
貨號：

CSB-EP022896MO1-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Stx1b重組蛋白
貨號：

CSB-BP022896MO1
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Stx1b重組蛋白
貨號：

CSB-MP022896MO1
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Stx1b
Uniprot No.：

P61264
別名：

Stx1b; Stx1b1; Stx1b2; Syntaxin-1B
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
基因功能參考文獻：
1. Stx1b+/- mice exhibited reduced GABA release both in vitro and in vivo, disrupting the DAergic system in the CNS. Stx1b+/- mice exhibited reduced pre-pulse inhibition. PMID: 29139159
2. Results demonstrated that STX1B is essential for the survival of neurons in vitro and it is a critical syntaxin protein for the neurotransmission at the mouse neuromuscular junctions PMID: 26203110
3. STX1B was important for neuronal survival, possibly by regulating the secretion of neurotrophic factors PMID: 24666284
4. closed conformation of syntaxin-1 gates the initiation of the synaptic vesicle fusion reaction, which is then mediated by SNARE-complex/Munc18-1 assemblies PMID: 18703708
亞細胞定位：

Membrane; Single-pass type IV membrane protein.
蛋白家族：

Syntaxin family
數據庫鏈接：

KEGG: mmu:56216

STRING: 10090.ENSMUSP00000101874

UniGene: Mm.439759