Recombinant Mouse Homeobox protein Hox-B5 (Hoxb5)

中文名稱：

小鼠Hoxb5重組蛋白
貨號：

CSB-YP010665MO
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Hoxb5重組蛋白
貨號：

CSB-EP010665MO
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Hoxb5重組蛋白
貨號：

CSB-EP010665MO-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Hoxb5重組蛋白
貨號：

CSB-BP010665MO
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Hoxb5重組蛋白
貨號：

CSB-MP010665MO
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Hoxb5
Uniprot No.：

P09079
別名：

Hoxb5; Hox-2.1; Hoxb-5; Homeobox protein Hox-B5; Homeobox protein H24.1; Homeobox protein Hox-2.1; Homeobox protein Mu-1
種屬：

Mus musculus (Mouse)
蛋白長度：

Full length protein
表達區(qū)域：

1-269
氨基酸序列

MSSYFVNSFS GRYPNGPDYQ LLNYGSGSSL SGSYRDPAAM HTGSYGYNYN GMDLSVNRSS ASSSHFGAVG ESSRAFPASA QEPRFRQATS SCSLSSPESL PCTNGDSHGA KPSASSPSDQ ATPASSSANF TEIDEASASS EPEEAASQLS SPSLARAQPE PMATSTAAPE GQTPQIFPWM RKLHISHDMT GPDGKRARTA YTRYQTLELE KEFHFNRYLT RRRRIEIAHA LCLSERQIKI WFQNRRMKWK KDNKLKSMSL ATAGSAFQP
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
基因功能參考文獻：
1. only the Hoxb5(+) hematopoietic stem cells exhibit long-term reconstitution capacity after transplantation in primary transplant recipients and, notably, in secondary recipients PMID: 26863982
2. The dysregulation of Hoxb5 signaling and early depletion of Neural crest cells contribute to enteric nervous system defect and other neurocristopathies in Hirschsprung disease patients deserves further investigation. PMID: 24141719
3. TGF beta inhibition enhanced airway branching, and Hoxb5 protein cellular localization was more diffuse. PMID: 24078914
4. HoxB5 is necessary and sufficient to activate the cell-intrinsic events that regulate the differentiation of angioblasts and mature endothelial cells from their mesoderm-derived precursors PMID: 12897140
5. Ret is a downstream target of Hoxb5 whose perturbation causes Ret haploinsufficiency, impaired NCC migration, and hypo/aganglionosis, suggesting that Hoxb5 may contribute to the etiology of Hirschsprung's disease. PMID: 18395091
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亞細胞定位：

Nucleus.
蛋白家族：

Antp homeobox family
組織特異性：

Expressed in a broad spectrum of tissues.
數(shù)據(jù)庫鏈接：

KEGG: mmu:15413

STRING: 10090.ENSMUSP00000035423

UniGene: Mm.207