Recombinant Mouse FAS-associated factor 2 (Faf2)

中文名稱：

小鼠Faf2重組蛋白
貨號：

CSB-YP662305MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Faf2重組蛋白
貨號：

CSB-EP662305MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Faf2重組蛋白
貨號：

CSB-EP662305MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Faf2重組蛋白
貨號：

CSB-BP662305MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Faf2重組蛋白
貨號：

CSB-MP662305MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Faf2
Uniprot No.：

Q3TDN2
別名：

Faf2; Kiaa0887; Ubxd8FAS-associated factor 2; UBX domain-containing protein 8
種屬：

Mus musculus (Mouse)
蛋白長度：

Full Length of Mature Protein
表達區域：

2-445
氨基酸序列

AAPEEQDLT QEQTEKLLQF QDLTGIESME QCRLALEQHN WNMEAAVQDR LNEQEGVPSV FNPPPARPLQ VNTADHRIYS YVVSRPQPRG LLGWGYYLIM LPFRFTYYTI LDIFRFALRF IRPDPRSRVT DPVGDIVSFM HSFEEKYGRA HPVFYQGTYS QALNDAKREL RFLLVYLHGD DHQDSDEFCR NALCAPEVIS LINSRMLFWA CSTNKPEGYR VSQALRENTY PFLAMIMLKD RRMTVVGRLE GLIQPDDLIN QLTFIMDANQ TYLVSERLER EERNQTQVLR QQQDEAYLAS LRADQEKERK KREEKERKRR KEEEVQQQKL AEERRRQNLQ EEKERKLECL PPEPSPDDPE SVKIIFKLPN DSRVERRFHF SQSLTVIHDF LFSLKESPEK FQIEANFPRR VLPCVPSEEW PNPPTLQEAG LSHTEVLFVQ DLTDE
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Plays an important role in endoplasmic reticulum-associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. By controlling the steady-state expression of the IGF1R receptor, indirectly regulates the insulin-like growth factor receptor signaling pathway. Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis.
基因功能參考文獻：
1. The results indicate that although UBXD8 functionality can be largely compensated in the normal setting, it is crucial to sustain VLDL secretion when exposed to a dietary challenge of high fat. PMID: 28421320
2. Depletion of UBXD8 in hepatocytes suppresses VLDL secretion, and could lead to periportal steatosis when mice are fed a high-fat diet. PMID: 25970332
亞細胞定位：

Cytoplasm. Lipid droplet. Endoplasmic reticulum.
數據庫鏈接：

KEGG: mmu:76577

STRING: 10090.ENSMUSP00000121182

UniGene: Mm.194459