Recombinant Human Semaphorin-3G (SEMA3G)

中文名稱：

人SEMA3G重組蛋白
貨號：

CSB-YP885719HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人SEMA3G重組蛋白
貨號：

CSB-EP885719HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人SEMA3G重組蛋白
貨號：

CSB-EP885719HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人SEMA3G重組蛋白
貨號：

CSB-BP885719HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

SEMA3G
Uniprot No.：

Q9NS98
別名：

FLJ00014; MGC119473; Sem2; SEM3G_HUMAN; Sema domain immunoglobulin domain (Ig) short basic domain secreted (semaphorin) 3G; Sema3g; Semaphorin 3G; Semaphorin sem2; Semaphorin-3G
種屬：

Homo sapiens (Human)
蛋白長度：

Full Length of Mature Protein
表達區域：

23-782
氨基酸序列

GPSPGPSV PRLRLSYRDL LSANRSAIFL GPQGSLNLQA MYLDEYRDRL FLGGLDALYS LRLDQAWPDP REVLWPPQPG QREECVRKGR DPLTECANFV RVLQPHNRTH LLACGTGAFQ PTCALITVGH RGEHVLHLEP GSVESGRGRC PHEPSRPFAS TFIDGELYTG LTADFLGREA MIFRSGGPRP ALRSDSDQSL LHDPRFVMAA RIPENSDQDN DKVYFFFSET VPSPDGGSNH VTVSRVGRVC VNDAGGQRVL VNKWSTFLKA RLVCSVPGPG GAETHFDQLE DVFLLWPKAG KSLEVYALFS TVSAVFQGFA VCVYHMADIW EVFNGPFAHR DGPQHQWGPY GGKVPFPRPG VCPSKMTAQP GRPFGSTKDY PDEVLQFARA HPLMFWPVRP RHGRPVLVKT HLAQQLHQIV VDRVEAEDGT YDVIFLGTDS GSVLKVIALQ AGGSAEPEEV VLEELQVFKV PTPITEMEIS VKRQMLYVGS RLGVAQLRLH QCETYGTACA ECCLARDPYC AWDGASCTHY RPSLGKRRFR RQDIRHGNPA LQCLGQSQEE EAVGLVAATM VYGTEHNSTF LECLPKSPQA AVRWLLQRPG DEGPDQVKTD ERVLHTERGL LFRRLSRFDA GTYTCTTLEH GFSQTVVRLA LVVIVASQLD NLFPPEPKPE EPPARGGLAS TPPKAWYKDI LQLIGFANLP RVDEYCERVW CRGTTECSGC FRSRSRGKQA RGKSWAGLEL GKKMKSRVHA EHNRTPREVE AT
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Has chemorepulsive activities for sympathetic axons. Ligand of NRP2.
基因功能參考文獻：
1. Results indicate that Sema3G protein is secreted by podocytes and protects them from inflammatory kidney diseases and diabetic nephropathy. PMID: 27180624
2. Results identify Sema3g as one of the downstream effectors of PPAR-gamma, which is centrally involved in regulating endothelial cell migration. PMID: 25335934
3. overexpressed SEMA3G inhibited the migratory and invasive behavior of U251MG cancer cells PMID: 22562223
4. Identify Sema3G as a primarily endothelial cell-expressed class 3 semaphorin that controls endothelial and smooth muscle cell functions in autocrine and paracrine manners. PMID: 20947821
5. In gliomas, SEMA3B, SEMA3G and NRP2 expressions were related to prolonged survival PMID: 18781179
6. Sema3G inhibits tumor progression from MDA-MB-435 but not from MDA-MB-231 cancer cells. It inhibits tumor angiogenesis in MDA-MB-231 cells. PMID: 18818766
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亞細胞定位：

Secreted.
蛋白家族：

Semaphorin family
數據庫鏈接：

HGNC: 30400

KEGG: hsa:56920

STRING: 9606.ENSP00000231721

UniGene: Hs.59729