Recombinant Human Echinoderm microtubule-associated protein-like 2 (EML2)

中文名稱：

人EML2重組蛋白
貨號：

CSB-YP007643HU
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人EML2重組蛋白
貨號：

CSB-EP007643HU-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人EML2重組蛋白
貨號：

CSB-BP007643HU
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人EML2重組蛋白
貨號：

CSB-MP007643HU
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

EML2
Uniprot No.：

O95834
別名：

1600029N02Rik; Echinoderm microtubule associated protein like 2; Echinoderm microtubule-associated protein-like 2; Echinoderm MT associated protein like protein 70; ELP70; EMAL2_HUMAN; EMAP-2; EMAP2; EML2; HuEMAP-2
種屬：

Homo sapiens (Human)
蛋白長度：

Full length protein
表達區(qū)域：

1-649
氨基酸序列

MSSFGAGKTK EVIFSVEDGS VKMFLRGRPV PMMIPDELAP TYSLDTRSEL PSCRLKLEWV YGYRGRDCRA NLYLLPTGEI VYFVASVAVL YSVEEQRQRH YLGHNDDIKC LAIHPDMVTI ATGQVAGTTK EGKPLPPHVR IWDSVSLSTL HVLGLGVFDR AVCCVGFSKS NGGNLLCAVD ESNDHMLSVW DWAKETKVVD VKCSNEAVLV ATFHPTDPTV LITCGKSHIY FWTLEGGSLS KRQGLFEKHE KPKYVLCVTF LEGGDVVTGD SGGNLYVWGK GGNRITQAVL GAHDGGVFGL CALRDGTLVS GGGRDRRVVL WGSDYSKLQE VEVPEDFGPV RTVAEGHGDT LYVGTTRNSI LQGSVHTGFS LLVQGHVEEL WGLATHPSRA QFVTCGQDKL VHLWSSDSHQ PLWSRIIEDP ARSAGFHPSG SVLAVGTVTG RWLLLDTETH DLVAIHTDGN EQISVVSFSP DGAYLAVGSH DNLVYVYTVD QGGRKVSRLG KCSGHSSFIT HLDWAQDSSC FVTNSGDYEI LYWDPATCKQ ITSADAVRNM EWATATCVLG FGVFGIWSEG ADGTDINAVA RSHDGKLLAS ADDFGKVHLF SYPCCQPRAL SHKYGGHSSH VTNVAFLWDD SMALTTGGKD TSVLQWRVV
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Tubulin binding protein that inhibits microtubule nucleation and growth, resulting in shorter microtubules.
基因功能參考文獻：
1. We have determined crystal structures of the coiled-coils from EML2 and EML4, which describe the structural basis of both EML self-association and oncogenic EML4-ALK activation. PMID: 25740311
2. Both EMAP II and CXCR3 were essentially required for gp120-induced lung microvascular endothelial cell apoptosis. PMID: 24318111
亞細胞定位：

Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Note=Colocalizes with the microtubule cytoskeleton. Colocalizes with the mitotic spindle.
蛋白家族：

WD repeat EMAP family
組織特異性：

Ubiquitous.
數(shù)據(jù)庫鏈接：

HGNC: 18035

OMIM: 617494

KEGG: hsa:24139

STRING: 9606.ENSP00000442365

UniGene: Hs.24178