Recombinant Goat Cholesterol side-chain cleavage enzyme, mitochondrial (CYP11A1)

中文名稱：

Recombinant Goat Cholesterol side-chain cleavage enzyme, mitochondrial(CYP11A1)
貨號：

CSB-YP006389GO
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Goat Cholesterol side-chain cleavage enzyme, mitochondrial(CYP11A1)
貨號：

CSB-EP006389GO
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Goat Cholesterol side-chain cleavage enzyme, mitochondrial(CYP11A1)
貨號：

CSB-EP006389GO-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Goat Cholesterol side-chain cleavage enzyme, mitochondrial(CYP11A1)
貨號：

CSB-BP006389GO
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Goat Cholesterol side-chain cleavage enzyme, mitochondrial(CYP11A1)
貨號：

CSB-MP006389GO
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

CYP11A1
Uniprot No.：

P79153
別名：

CYP11A1Cholesterol side-chain cleavage enzyme; mitochondrial; EC 1.14.15.6; CYPXIA1; Cholesterol desmolase; Cytochrome P450 11A1; Cytochrome P450(scc)
種屬：

Capra hircus (Goat)
蛋白長度：

Full Length of Mature Protein
表達區(qū)域：

40-520
氨基酸序列

I STRTPRPYSE IPSPGDNGWI NLYHFWRKKS SQRIHFRHIE NFQKYGPIYR EKLGNLESVY IIHPEDVAHL FKFEGSYPQR YDIPPWLAYH QYYQKPIGVL FKKSGAWKKD RVVLNTEVMA PEAIKNFIPL LNPVSQDFVS LLRKRIQQQG SGKFAGDIKE DLFHFAFESI TNVMFGERLG MLEDTVNTEA QKFIDAVYKM FHTSVPLLNL PPELYRLFRT KTWRDHVAAW DTIFNKAEKY TEIFYQDLRQ KTEFRNYPGI LYHLLKSEKM LLEDVKANIT EMLAGGVDTT SMTLQWHLYE MARSLNVQEM LREEVLNARR QAEGDISKML QMVPLLKASI KETLRLHPIS VTLQRYPESD LVLQDYLIPA KTLVQVAIYA MGRDPAFFSN PDKFDPTRWL GKDKDLIHFR NLGFGWGVRQ CVGRRIAELE MTLFLIHILE NFKIEMQQIG DVNTIFNLIL TPDKPIFLVF RPFNQDPPQA
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
亞細(xì)胞定位：

Mitochondrion inner membrane; Peripheral membrane protein.
蛋白家族：

Cytochrome P450 family
數(shù)據(jù)庫鏈接：

KEGG: chx:102173131

UniGene: Chi.38574