Recombinant Cricetulus griseus Multidrug resistance protein 1 (ABCB1), partial

中文名稱：

Recombinant Cricetulus griseus Multidrug resistance protein 1(ABCB1) ,partial
貨號：

CSB-YP001046DXU
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Cricetulus griseus Multidrug resistance protein 1(ABCB1) ,partial
貨號：

CSB-EP001046DXU
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Cricetulus griseus Multidrug resistance protein 1(ABCB1) ,partial
貨號：

CSB-EP001046DXU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Cricetulus griseus Multidrug resistance protein 1(ABCB1) ,partial
貨號：

CSB-BP001046DXU
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Cricetulus griseus Multidrug resistance protein 1(ABCB1) ,partial
貨號：

CSB-MP001046DXU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

ABCB1
Uniprot No.：

P21448
別名：

ABCB1; PGP1; PGY1; ATP-dependent translocase ABCB1; ATP-binding cassette sub-family B member 1; Multidrug resistance protein 1; EC 7.6.2.2; P-glycoprotein 1; Phospholipid transporter ABCB1; EC 7.6.2.1; CD antigen CD243
種屬：

Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins. Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
基因功能參考文獻：
1. Novel function: ABCB1 is involved in sebum secretion in the insulin-differentiated hamster sebocytes, which is associated with non-apoptotic phosphatidylserine exposure and the increased level of intracellular ATP. PMID: 21889999
亞細胞定位：

Cell membrane; Multi-pass membrane protein. Apical cell membrane.
蛋白家族：

ABC transporter superfamily, ABCB family, Multidrug resistance exporter (TC 3.A.1.201) subfamily
組織特異性：

Expressed at a higher level in intestines than in kidney and liver.
數據庫鏈接：

KEGG: cge:100682536