Recombinant Bovine Insulin-like 3 (INSL3), partial

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中文名稱：

牛INSL3重組蛋白
貨號：

CSB-EP011747BO
說明書：

MSDS Datasheet
規格：

￥1536
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

Greater than 90% as determined by SDS-PAGE.
基因名：

INSL3
Uniprot No.：

O77801
種屬：

Bos taurus (Bovine)
蛋白長度：

Partial
來源：

E.coli
分子量：

20.1 kDa
表達區域：

22-66aa
氨基酸序列

GPAAAQEAPEKLCGHHFVRALVRLCGGPRWSSEEDGRPVAGGDRE
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 6xHis-KSI-tagged
產品提供形式：

Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

3-7 business days
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.
基因功能參考文獻：
1. These results suggest that reduced secretions of IGF-I, INSL3, and inhibin surrounding puberty may be associated with semen aberration in beef bulls. PMID: 29597124
2. These results suggested an acute regulation of INSL3 by luteinizing hormone (LH) because INSL3 concentrations increased immediately after endogenous and exogenous LH stimulation. PMID: 26318230
3. INSL3 plays a luteotropic role as a local regulator in the bovine corpus luteum. PMID: 23220928
4. BMP6 has a role in downregulating INSL3 and CYP17A1 and other proteins that modulate ovarian androgen production PMID: 23530236
5. The likely role of INSL3 as an important intrafollicular modulator of thecal interna cell function/steroidogenesis. PMID: 23546605
6. INSL3 provides the first example of a gender-specific fetal hormone with the potential to influence both placental and maternal physiology PMID: 21603619
7. relaxin-like factor mRNA was highly expressed in the corpus luteum on days 7 and 14 of pregnancy PMID: 15956752
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亞細胞定位：

Secreted.
蛋白家族：

Insulin family
組織特異性：

Expressed exclusively in Leydig cells of the testis.
數據庫鏈接：

KEGG: bta:281870

STRING: 9913.ENSBTAP00000027848

UniGene: Bt.91145