Recombinant Arabidopsis thaliana Serine/threonine-protein kinase ATM (ATM), partial

中文名稱：

Recombinant Arabidopsis thaliana Serine/threonine-protein kinase ATM(ATM) ,partial
貨號(hào)：

CSB-YP885532DOA
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Arabidopsis thaliana Serine/threonine-protein kinase ATM(ATM) ,partial
貨號(hào)：

CSB-EP885532DOA
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Arabidopsis thaliana Serine/threonine-protein kinase ATM(ATM) ,partial
貨號(hào)：

CSB-EP885532DOA-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Arabidopsis thaliana Serine/threonine-protein kinase ATM(ATM) ,partial
貨號(hào)：

CSB-BP885532DOA
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Arabidopsis thaliana Serine/threonine-protein kinase ATM(ATM) ,partial
貨號(hào)：

CSB-MP885532DOA
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

ATM
Uniprot No.：

Q9M3G7
別名：

ATM; At3g48190; T24C20.70Serine/threonine-protein kinase ATM; EC 2.7.11.1; Ataxia telangiectasia mutated homolog; AtATM
種屬：

Arabidopsis thaliana (Mouse-ear cress)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR) or DNA replication stalling. Plays a central role in the perception and response to both stress-induced damage in somatic cells and developmentally programmed DNA damage during meiosis. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone variant H2AX to form H2AXS139ph at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Involved in transcriptional regulation of RAD51, PARP1, GR1, and LIG4 in response to DNA double strand breaks. Plays a dual role by activating the DNA damage response at dysfunctional telomeres and yet preventing this activation at functional telomeres. Not required for telomere length homeostasis. Regulates DNA damage response (DDR) synergistically with RUG3. Together with RUG3, involved in the splicing of the ND2/NAD2 mRNA.
亞細(xì)胞定位：

Nucleus.
蛋白家族：

PI3/PI4-kinase family
組織特異性：

Ubiquitously expressed at low levels with slightly higher levels in flower buds.
數(shù)據(jù)庫(kù)鏈接：

STRING: 3702.AT3G48190.1