UFC1 Recombinant Monoclonal Antibody
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中文名稱：UFC1 Recombinant Monoclonal Antibody
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貨號：CSB-RA634478A0HU
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規格：￥1320
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圖片：
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Flow cytometric analysis of UFC1 expression in HeLa cells using UFC1 antibody. Green, isotype control; red, UFC1. -
Immunocytochemical staining of HeLa cells with UFC1 antibody. Nuclei were stained blue with DAPI; UFC1 was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Low. Scale bar, 20 μm. -
Western blotting analysis using UFC1 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with UFC1 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
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其他：
產品詳情
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Uniprot No.：
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基因名：UFC1
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別名：UFC1; Ubiquitin-Fold Modifier Conjugating Enzyme 1; HSPC155; Ubiquitin-Fold Modifier-Conjugating Enzyme 1; Ufm1-Conjugating Enzyme 1; NEDSG
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反應種屬：Human
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免疫原：Recombinant Human UFC1 protein
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Monoclonal
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抗體亞型：Rabbit IgG
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純化方式：Affinity-chromatography
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克隆號：15A9
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：ELISA, WB, FC, ICC
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 FC 1:200-1:2000 ICC 1:100-1:1000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：E1-like enzyme which specifically catalyzes the second step in ufmylation. Accepts the ubiquitin-like modifier UFM1 from the E1 enzyme UBA5 and forms an intermediate with UFM1 via a thioester linkage. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.
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基因功能參考文獻：
- that UFC1 regulates survival of Osteoarthritis chondrocytes through physically association with miR-34a PMID: 27529373
- Autoantibodies binding to Ufc1 were found in 19 of 29 patients (66%) with active mycobacterial infections. PMID: 25213431
- Uba5 residues 364-404 were demonstrated to be necessary for the transthiolation of Ufm1 to Ufc1, and Uba5 381-404 was identified to be the minimal region for Ufc1 recognition PMID: 25084390
- UFC1 interact with the mRNA stabilizing protein HuR to increase levels of beta-catenin in hepatocellular carcinoma. PMID: 25449213
- NCAM140 interacts with ufc1 and its trafficking and endocytosis is upregulated in the presense of Ufm1. PMID: 24726913
- The structure of human Ufc1 was solved by using both NMR spectroscopy and X-ray crystallography PMID: 19101823
- Identification of a novel enzyme called UFC1 for Ufm1-conjugating enzyme 1. PMID: 15071506
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蛋白家族：Ubiquitin-conjugating enzyme family, UFC1 subfamily
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數據庫鏈接：
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