NOP10 Recombinant Monoclonal Antibody
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中文名稱：NOP10 Recombinant Monoclonal Antibody
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貨號：CSB-RA251847A0HU
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規格：￥1320
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圖片：
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Flow cytometric analysis of NOP10 expression in HepG2 cells using NOP10 antibody. Green, isotype control; red, NOP10. -
Immunocytochemical staining of HepG2 cells with NOP10 antibody. Nuclei were stained blue with DAPI; NOP10 was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 μm. -
Western blotting analysis using NOP10 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with NOP10 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
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其他：
產品詳情
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Uniprot No.：
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基因名：NOP10
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別名：NOP10; NOP10 Ribonucleoprotein; NOP10P; NOLA3; Nucleolar Protein Family A, Member 3 (H/ACA Small Nucleolar RNPs); H/ACA Ribonucleoprotein Complex Subunit 3; Nucleolar Protein Family A Member 3; Homolog Of Yeast Nop10p; Nucleolar Protein 10; SnoRNP Protein NOP10; MGC70651; NOP10 Ribonucleoprotein Homolog (Yeast); NOP10 Ribonucleoprotein Homolog; PFBMFT9; CHINE2; DKCB1
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反應種屬：Human, Mouse, Rat
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免疫原：Recombinant Human NOP10 protein
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Monoclonal
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抗體亞型：Rabbit IgG
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純化方式：Affinity-chromatography
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克隆號：4B4
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：ELISA, WB, FC, ICC
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 FC 1:200-1:2000 ICC 1:100-1:1000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
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基因功能參考文獻：
- Indian aplastic anemia patients did not have NOP10 mutations. PMID: 25906515
- Effects of dyskeratosis congenita mutations in NOP10 on assembly of H/ACA pre-RNPs PMID: 20008900
- NOP10 has a role in the telomerase complex and telomere maintenance, and in autosomal recessive dyskeratosis congenita PMID: 17507419
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相關疾病：Dyskeratosis congenita, autosomal recessive, 1 (DKCB1)
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亞細胞定位：Nucleus, nucleolus. Nucleus, Cajal body. Note=Also localized to Cajal bodies (coiled bodies).
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蛋白家族：NOP10 family
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數據庫鏈接：
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