ZNF274 Antibody, HRP conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) ZNF274 Polyclonal antibody
Uniprot No.：

Q96GC6
基因名：

ZNF274
別名：

ZNF274 antibody; ZKSCAN19 antibody; SP2114Neurotrophin receptor-interacting factor homolog antibody; Zinc finger protein 274 antibody; Zinc finger protein HFB101 antibody; Zinc finger protein with KRAB and SCAN domains 19 antibody; Zinc finger protein zfp2 antibody; Zf2 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Neurotrophin receptor-interacting factor homolog protein (1-320AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Probable transcription repressor. Specifically binds to the 3'-end of zinc-finger coding genes and recruiting chromatin-modifying proteins such as SETDB1 and TRIM28/KAP1, leading to transcription repression. The SETDB1-TRIM28-ZNF274 complex may play a role in recruiting ATRX to the 3'-exons of zinc-finger coding genes with atypical chromatin signatures to establish or maintain/protect H3K9me3 at these transcriptionally active regions.
基因功能參考文獻：
1. A proximal promoter construct for the MAS gene was repressed by the SOX [SRY (sex-determining region on the Y chromosome) box] proteins SRY, SOX2, SOX3 and SOX14, of which SRY is known to interact with the KRAB domain. PMID: 24128372
亞細胞定位：

Cytoplasm. Nucleus, nucleolus.
蛋白家族：

Krueppel C2H2-type zinc-finger protein family
數據庫鏈接：

HGNC: 13068

OMIM: 605467

KEGG: hsa:10782

STRING: 9606.ENSP00000321209

UniGene: Hs.83761

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