ZKSCAN4 Antibody

說明書

中文名稱：

ZKSCAN4兔多克隆抗體
貨號：

CSB-PA005456
規格：

￥1090
圖片：
Western Blot analysis of MCF7 HepG2 293 mouse brain mouse lung cells using ZKSCAN4 Polyclonal Antibody
其他：

產品詳情

Uniprot No.：

Q969J2
基因名：

ZKSCAN4
別名：

FLJ32136 antibody; P1P373C6 antibody; p373c6.1 (novel C2H2 type zinc finger protein) antibody; P373c6.1 antibody; Zinc finger protein 307 antibody; Zinc finger protein 427 antibody; Zinc finger protein with KRAB and SCAN domains 4 antibody; Zinc finger with KRAB and SCAN domains 4 antibody; ZKSC4_HUMAN antibody; ZKSCAN4 antibody; ZNF427 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Synthesized peptide derived from the Internal region of Human ZKSCAN4.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:20000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May be involved in the transcriptional activation of MDM2 and EP300 genes.
基因功能參考文獻：
1. our results indicate that ZNF307 may serve as a tumor suppressor and inhibits cell proliferation of hepatocellular carcinoma via inducing apoptosis PMID: 28765950
2. ZNF307 ameliorates pressure overload-induced cardiac hypertrophy by inhibiting the activity of NF-kappaB-signaling pathway PMID: 28223477
3. ZNF307 might suppress p53-p21 pathway through activating MDM2 and EP300 expression and inducing p53 degradation PMID: 17910948
4. The SCAN- and KRAB-domain-containing zinc finger protein 307 (ZKSCAN4) was co-precipitated with the receptor when both proteins were overexpressed in HEK293 cells. PMID: 19008334
亞細胞定位：

Nucleus.
蛋白家族：

Krueppel C2H2-type zinc-finger protein family
組織特異性：

Expressed in adult heart, brain, placenta, lung and kidney, but not in adult liver and skeletal muscle. In 17-day old embryo, detected in liver, skeletal muscle, brain, heart and small intestine.
數據庫鏈接：

HGNC: 13854

OMIM: 611643

KEGG: hsa:387032

STRING: 9606.ENSP00000366509

UniGene: Hs.44720

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