ZKSCAN4 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) ZKSCAN4 Polyclonal antibody
Uniprot No.：

Q969J2
基因名：

ZKSCAN4
別名：

FLJ32136 antibody; P1P373C6 antibody; p373c6.1 (novel C2H2 type zinc finger protein) antibody; P373c6.1 antibody; Zinc finger protein 307 antibody; Zinc finger protein 427 antibody; Zinc finger protein with KRAB and SCAN domains 4 antibody; Zinc finger with KRAB and SCAN domains 4 antibody; ZKSC4_HUMAN antibody; ZKSCAN4 antibody; ZNF427 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Zinc finger protein with KRAB and SCAN domains 4 protein (264-545AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May be involved in the transcriptional activation of MDM2 and EP300 genes.
基因功能參考文獻：
1. our results indicate that ZNF307 may serve as a tumor suppressor and inhibits cell proliferation of hepatocellular carcinoma via inducing apoptosis PMID: 28765950
2. ZNF307 ameliorates pressure overload-induced cardiac hypertrophy by inhibiting the activity of NF-kappaB-signaling pathway PMID: 28223477
3. ZNF307 might suppress p53-p21 pathway through activating MDM2 and EP300 expression and inducing p53 degradation PMID: 17910948
4. The SCAN- and KRAB-domain-containing zinc finger protein 307 (ZKSCAN4) was co-precipitated with the receptor when both proteins were overexpressed in HEK293 cells. PMID: 19008334
亞細胞定位：

Nucleus.
蛋白家族：

Krueppel C2H2-type zinc-finger protein family
組織特異性：

Expressed in adult heart, brain, placenta, lung and kidney, but not in adult liver and skeletal muscle. In 17-day old embryo, detected in liver, skeletal muscle, brain, heart and small intestine.
數據庫鏈接：

HGNC: 13854

OMIM: 611643

KEGG: hsa:387032

STRING: 9606.ENSP00000366509

UniGene: Hs.44720

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