ZDHHC5 Antibody, HRP conjugated

說(shuō)明書

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) ZDHHC5 Polyclonal antibody
Uniprot No.：

Q9C0B5
基因名：

ZDHHC5
別名：

ZDHHC5; KIAA1748; ZNF375; Palmitoyltransferase ZDHHC5; Zinc finger DHHC domain-containing protein 5; DHHC-5; Zinc finger protein 375
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Palmitoyltransferase ZDHHC5 protein (231-500AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and is involved in a variety of cellular processes. Palmitoylates the G-protein coupled receptor SSTR5 and for FLOT2.
基因功能參考文獻(xiàn)：
1. High ZDHHC5 expression is associated with Glioma. PMID: 28775165
2. Data indicate that DHHC5 has oncogenic capacity and contributes to tumor formation in non-small cell lung cancer. PMID: 25573953
3. ZDHHC5 and SSTR5 are colocalized at the plasma membrane and coexpression of ZDHHC5 increased palmitoylation of SSTR5 whereas knock-down of endogenous ZDHHC5 by siRNAs decreased it. PMID: 21820437
4. Data show that palmitoyl acyltransferases DHHC5, DHHC6, and DHHC8 appear to be S-acylated on three cysteine residues within a novel CCX(7-13)C(S/T) motif downstream of a conserved Asp-His-His-Cys cysteine-rich domain. PMID: 19801377
亞細(xì)胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

DHHC palmitoyltransferase family, ERF2/ZDHHC9 subfamily
數(shù)據(jù)庫(kù)鏈接：

HGNC: 18472

OMIM: 614586

KEGG: hsa:25921

STRING: 9606.ENSP00000287169

UniGene: Hs.27239

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