VAMP1 Antibody, Biotin conjugated

說明書

中文名稱：

VAMP1兔多克隆抗體, Biotin偶聯
貨號：

CSB-PA025780LD01HU
規格：

￥880
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) VAMP1 Polyclonal antibody
Uniprot No.：

P23763
基因名：

VAMP1
別名：

VAMP1; SYB1; Vesicle-associated membrane protein 1; VAMP-1; Synaptobrevin-1
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Vesicle-associated membrane protein 1 protein (1-96AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Involved in the targeting and/or fusion of transport vesicles to their target membrane.
基因功能參考文獻：
1. VAMP1 homozygous mutations causes of presynaptic congenital myasthenic syndrome. PMID: 28253535
2. residue 48 of VAMP1 varies frequently between M and I across seventeen closely related primate species, suggesting a potential selective pressure from members of BoNTs for resistance in vertebrates. PMID: 25010769
3. Genetically regulated VAMP1 expression in the brain may modify both Alzheimer's disease risk and may contribute to Alzheimer's pathophysiology PMID: 25881291
4. This report identifies vesicle-associated membrane protein 1 (VAMP1), which encodes a critical protein for synaptic exocytosis, as the responsible gene fora dominantly inherited spastic ataxia PMID: 22958904
5. multiple domains outside the R-SNARE of tomosyn are critical to the efficacy of inhibition by tomosyn on exocytotic secretion PMID: 21330375
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相關疾病：

Spastic ataxia 1, autosomal dominant (SPAX1)
亞細胞定位：

[Isoform 1]: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome.; [Isoform 2]: Cytoplasmic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome.; [Isoform 3]: Mitochondrion outer membrane; Single-pass type IV membrane protein.
蛋白家族：

Synaptobrevin family
組織特異性：

Nervous system, skeletal muscle and adipose tissue.
數據庫鏈接：

HGNC: 12642

OMIM: 108600

KEGG: hsa:6843

STRING: 9606.ENSP00000379602

UniGene: Hs.20021

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