UBA7 Antibody

中文名稱：

UBA7兔多克隆抗體
貨號：

CSB-PA025421LA01HU
規格：

￥440
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) UBA7 Polyclonal antibody
Uniprot No.：

P41226
基因名：

UBA7
別名：

D8 antibody; MGC12713 antibody; UBA1, ubiquitin activating enzyme E1 homolog B antibody; UBA1B antibody; UBA7 antibody; UBA7, ubiquitin activating enzyme E1 antibody; UBA7_HUMAN antibody; Ube 1L antibody; UBE 2 antibody; UBE1L antibody; UBE2 antibody; Ubiquitin activating enzyme 2 antibody; Ubiquitin activating enzyme E1 homolog antibody; Ubiquitin Activating Enzyme E1 Like antibody; Ubiquitin activating enzyme E1 related protein antibody; Ubiquitin-activating enzyme 7 antibody; Ubiquitin-activating enzyme E1 homolog antibody; ubiquitin-activating enzyme-2 antibody; ubiquitin-like modifier activating enzyme 7 antibody; Ubiquitin-like modifier-activating enzyme 7 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Ubiquitin-like modifier-activating enzyme 7 protein (1-265AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，UBA7 Antibody (CSB-PA025421LA01HU)，的標記方式是Non-conjugated。對于UBA7 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA025421LB01HU	UBA7 Antibody, HRP conjugated	ELISA
FITC	CSB-PA025421LC01HU	UBA7 Antibody, FITC conjugated
Biotin	CSB-PA025421LD01HU	UBA7 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Activates ubiquitin by first adenylating with ATP its C-terminal glycine residue and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Catalyzes the ISGylation of influenza A virus NS1 protein.
基因功能參考文獻：
1. RNF170, an endoplasmic reticulum (ER)-associated ubiquitin E3 ligase, interacted with pUL50 and promoted pUL50-mediated UBE1L degradation via ubiquitination. PMID: 29743376
2. the cellular effects of progerin expression in Hutchinson-Gilford progeria syndrome are transduced, at least in part, through reduced function of the Ran GTPase and E2 SUMOylation pathways. PMID: 21670151
3. Observational study and meta-analysis of gene-disease association. (HuGE Navigator) PMID: 20601676
4. UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia PMID: 11891284
5. RA treatment of APL and other RA-responsive leukemic cells induced expression of UBE1L and ISG15 as well as intracellular ISG15 conjugates. A physical association was found between UBE1L and ISG15 in vivo. PMID: 14976209
6. Ube1L was required for transfer of ISG15 to UbcH8 and for binding of Ube1L to UbcH8 PMID: 18583345
7. UBE1L-ISG15 preferentially inhibits cyclin D1 in lung cancer PMID: 19074853
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蛋白家族：

Ubiquitin-activating E1 family
組織特異性：

Expressed in a variety of normal and tumor cell types, but is reduced in lung cancer cell lines.
數據庫鏈接：

HGNC: 12471

OMIM: 191325

KEGG: hsa:7318

STRING: 9606.ENSP00000333266

UniGene: Hs.16695

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