UBA7 Antibody
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中文名稱：UBA7兔多克隆抗體
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貨號：CSB-PA004359
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規格：￥1090
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圖片：
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Western Blot analysis of HeLa cells using UBE1L Polyclonal Antibody
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：D8 antibody; MGC12713 antibody; UBA1, ubiquitin activating enzyme E1 homolog B antibody; UBA1B antibody; UBA7 antibody; UBA7, ubiquitin activating enzyme E1 antibody; UBA7_HUMAN antibody; Ube 1L antibody; UBE 2 antibody; UBE1L antibody; UBE2 antibody; Ubiquitin activating enzyme 2 antibody; Ubiquitin activating enzyme E1 homolog antibody; Ubiquitin Activating Enzyme E1 Like antibody; Ubiquitin activating enzyme E1 related protein antibody; Ubiquitin-activating enzyme 7 antibody; Ubiquitin-activating enzyme E1 homolog antibody; ubiquitin-activating enzyme-2 antibody; ubiquitin-like modifier activating enzyme 7 antibody; Ubiquitin-like modifier-activating enzyme 7 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Synthesized peptide derived from the C-terminal region of Human UBE1L.
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：WB, IHC, ELISA
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:10000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Activates ubiquitin by first adenylating with ATP its C-terminal glycine residue and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Catalyzes the ISGylation of influenza A virus NS1 protein.
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基因功能參考文獻：
- RNF170, an endoplasmic reticulum (ER)-associated ubiquitin E3 ligase, interacted with pUL50 and promoted pUL50-mediated UBE1L degradation via ubiquitination. PMID: 29743376
- the cellular effects of progerin expression in Hutchinson-Gilford progeria syndrome are transduced, at least in part, through reduced function of the Ran GTPase and E2 SUMOylation pathways. PMID: 21670151
- Observational study and meta-analysis of gene-disease association. (HuGE Navigator) PMID: 20601676
- UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia PMID: 11891284
- RA treatment of APL and other RA-responsive leukemic cells induced expression of UBE1L and ISG15 as well as intracellular ISG15 conjugates. A physical association was found between UBE1L and ISG15 in vivo. PMID: 14976209
- Ube1L was required for transfer of ISG15 to UbcH8 and for binding of Ube1L to UbcH8 PMID: 18583345
- UBE1L-ISG15 preferentially inhibits cyclin D1 in lung cancer PMID: 19074853
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蛋白家族：Ubiquitin-activating E1 family
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組織特異性：Expressed in a variety of normal and tumor cell types, but is reduced in lung cancer cell lines.
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數據庫鏈接：
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