TRIM26 Antibody

中文名稱：

TRIM26兔多克隆抗體
貨號：

CSB-PA619638LA01HU
規(guī)格：

￥440
圖片：
IHC image of CSB-PA619638LA01HU diluted at 1:300 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) TRIM26 Polyclonal antibody
Uniprot No.：

Q12899
基因名：

TRIM26
別名：

Acid finger protein antibody; AFP antibody; CAM25547 antibody; RING finger protein 95 antibody; RNF95 antibody; TRI26_HUMAN antibody; TRIM26 antibody; tripartite motif containing 26 antibody; Tripartite motif-containing protein 26 antibody; widely expressed acid zinc finger protein antibody; Zinc finger protein 173 antibody; Zinc finger protein 173; formerly antibody; ZNF173 antibody; ZNF173; formerly antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Tripartite motif-containing protein 26 protein (151-270AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，TRIM26 Antibody (CSB-PA619638LA01HU)，的標記方式是Non-conjugated。對于TRIM26 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA619638LB01HU	TRIM26 Antibody, HRP conjugated	ELISA
FITC	CSB-PA619638LC01HU	TRIM26 Antibody, FITC conjugated
Biotin	CSB-PA619638LD01HU	TRIM26 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:200-1:500

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs). Promotes nuclear IRF3 ubiquitination and proteasomal degradation. Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1.
基因功能參考文獻：
1. Autoubiquitination of TRIM26 links TBK1 to NEMO in RLR-mediated innate antiviral immune response PMID: 26611359
2. Down-regulation of TRIM26 is associated with worse prognosis of hepatocellular carcinoma. PMID: 26043685
3. In addition to confirming one of the top findings in the meta-analysis, TRIM26, RNF5 and HLA-DRB3 have been identified as potential candidate genes for schizophrenia. PMID: 22433715
4. The study reports no associations between polymorphisms in TRIM26 and the risk of aspirin-exacerbated respiratory disease in both logistic and regression analyses. PMID: 22294275
亞細胞定位：

Cytoplasm. Nucleus.
蛋白家族：

TRIM/RBCC family
數(shù)據庫鏈接：

HGNC: 12962

OMIM: 600830

KEGG: hsa:7726

STRING: 9606.ENSP00000391879

UniGene: Hs.485041

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