TRIM26 Antibody, FITC conjugated
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中文名稱：TRIM26兔多克隆抗體, FITC偶聯(lián)
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貨號：CSB-PA619638LC01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) TRIM26 Polyclonal antibody
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Uniprot No.：
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基因名：TRIM26
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別名：Acid finger protein antibody; AFP antibody; CAM25547 antibody; RING finger protein 95 antibody; RNF95 antibody; TRI26_HUMAN antibody; TRIM26 antibody; tripartite motif containing 26 antibody; Tripartite motif-containing protein 26 antibody; widely expressed acid zinc finger protein antibody; Zinc finger protein 173 antibody; Zinc finger protein 173; formerly antibody; ZNF173 antibody; ZNF173; formerly antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Tripartite motif-containing protein 26 protein (151-270AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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功能：E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs). Promotes nuclear IRF3 ubiquitination and proteasomal degradation. Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1.
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基因功能參考文獻：
- Autoubiquitination of TRIM26 links TBK1 to NEMO in RLR-mediated innate antiviral immune response PMID: 26611359
- Down-regulation of TRIM26 is associated with worse prognosis of hepatocellular carcinoma. PMID: 26043685
- In addition to confirming one of the top findings in the meta-analysis, TRIM26, RNF5 and HLA-DRB3 have been identified as potential candidate genes for schizophrenia. PMID: 22433715
- The study reports no associations between polymorphisms in TRIM26 and the risk of aspirin-exacerbated respiratory disease in both logistic and regression analyses. PMID: 22294275
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亞細胞定位：Cytoplasm. Nucleus.
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蛋白家族：TRIM/RBCC family
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數(shù)據(jù)庫鏈接：
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