TMTC1 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) TMTC1 Polyclonal antibody
Uniprot No.：

Q8IUR5
基因名：

TMTC1
別名：

TMTC1 antibody; ARG99 antibody; Protein O-mannosyl-transferase TMTC1 antibody; EC 2.4.1.109 antibody; Transmembrane and TPR repeat-containing protein 1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Transmembrane and TPR repeat-containing protein 1 protein (1-227AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3.
基因功能參考文獻：
1. O-mannosylation pathway dedicated to cadherins/ protocadherins orchestrated by the four TMTC1-4 genes PMID: 28973932
2. findings provide an important link between aneuploidy and the stress pathways activated by Aurora B inhibition and also support the use of Aurora B inhibitors in combination therapy for treatment of cancer. PMID: 24764305
亞細胞定位：

Membrane; Multi-pass membrane protein. Endoplasmic reticulum.
蛋白家族：

TMTC family
數據庫鏈接：

HGNC: 24099

OMIM: 615855

KEGG: hsa:83857

STRING: 9606.ENSP00000442046

UniGene: Hs.401954

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