TMEM132D Antibody

中文名稱：

TMEM132D兔多克隆抗體
貨號：

CSB-PA023702LA01HU
規格：

￥440
圖片：
Immunofluorescence staining of HepG2 cells with CSB-PA023702LA01HU at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
其他：

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靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) TMEM132D Polyclonal antibody
Uniprot No.：

Q14C87
基因名：

TMEM132D
別名：

TMEM132D antibody; HBE120 antibody; KIAA1944 antibody; MOLT antibody; Transmembrane protein 132D antibody; Mature oligodendrocytes transmembrane protein antibody; Mature OL transmembrane protein antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Transmembrane protein 132D protein (796-909AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，TMEM132D Antibody (CSB-PA023702LA01HU)，的標記方式是Non-conjugated。對于TMEM132D Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA023702LB01HU	TMEM132D Antibody, HRP conjugated	ELISA
FITC	CSB-PA023702LC01HU	TMEM132D Antibody, FITC conjugated
Biotin	CSB-PA023702LD01HU	TMEM132D Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IF

推薦稀釋比：

Application	Recommended Dilution
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

May serve as a cell-surface marker for oligodendrocyte differentiation.
基因功能參考文獻：
1. Thus, GPC6 and TMEM132D may serve as predictors of CD8+ T-lymphocyte infiltration and as favorable prognostic markers in early stage ovarian cancer with important consequences for diagnosis. PMID: 26448945
2. TMEM132D, COMT and GABRA6 gene polymorphisms may influence susceptibility to panic disorder(PD) and major depressive disorder(MDD)in Japanese adults; these variants may increase vulnerability to PD by modulating oligodendrocytes and GABA and dopaminergic functions in related brain regions, altering neuronal processing of anxiety-related emotionl signals PMID: 25974322
3. Enhanced amygdala gray matter volumes and anxiety-related (but not panic-specific) personality profiles are found in healthy normal carriers of the rs11060369 AA TMEM132D genotype. PMID: 24495968
4. data suggest that not only common but also putatively functional and/or rare variants within TMEM132D might contribute to the risk to develop anxiety disorders PMID: 22911938
5. TMEM132D was first identified as a possible candidate gene for panic disorder in a genome-wide association study conducted at the Max Planck Institute of Psychiatry in Munich. PMID: 22948381
6. We found no genome-wide statistically significant associations but identified several plausible candidate genes among findings at p < 5E-05: TMEM132D, LRRC7, SEMA3A, ALK, and STIP1. PMID: 21784300
7. TMEM132D may be an important new candidate gene for PD as well as more generally for anxiety-related behavior. PMID: 20368705
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亞細胞定位：

Membrane; Single-pass type I membrane protein.
蛋白家族：

TMEM132 family
組織特異性：

Expressed in mature oligodendrocytes. Detected in the brain, lung, pancreas and testis.
數據庫鏈接：

HGNC: 29411

OMIM: 611257

KEGG: hsa:121256

STRING: 9606.ENSP00000408581

UniGene: Hs.507268

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