TMED3 Antibody

說明書

中文名稱：

TMED3兔多克隆抗體
貨號(hào)：

CSB-PA917113
規(guī)格：

￥1100
圖片：
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA917113(TMED3 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
其他：

產(chǎn)品詳情

Uniprot No.：

Q9Y3Q3
基因名：

TMED3
別名：

C15orf22 antibody; Integral type I protein antibody; Membrane protein p24B antibody; p24 family protein gamma 4 antibody; p24 family protein gamma-4 antibody; P24B antibody; p24g4 antibody; p24gamma4 antibody; p26 antibody; Testis tissue sperm binding protein Li 48e antibody; Tmed3 antibody; TMED3_HUMAN antibody; Transmembrane emp24 domain containing protein 3 antibody; Transmembrane emp24 domain-containing protein 3 antibody; Transmembrane p24 trafficking protein 3 antibody; UNQ5357/PRO1078 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Fusion protein of Human TMED3
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

Antigen affinity purification
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,IHC

推薦稀釋比：

Application	Recommended Dilution
ELISA	1:2000-1:5000
IHC	1:25-1:100

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network.
基因功能參考文獻(xiàn)：
1. Study demonstrates that transmembrane p24 trafficking protein 3 (TMED3) promotes hepatocellular carcinoma (HCC) metastasis and is a potential prognostic biomarker in hepatocellular carcinoma. Study propose that TMED3 promotes HCC metastasis through IL-11/STAT3 signaling. PMID: 27901021
2. This genome-wide screen has identified two novel metastatic suppressors: TMED3 and SOX12, the knockdown of which increases metastatic growth after direct seeding. PMID: 24920608
亞細(xì)胞定位：

Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Single-pass type I membrane protein.
蛋白家族：

EMP24/GP25L family
數(shù)據(jù)庫鏈接：

HGNC: 28889

KEGG: hsa:23423

STRING: 9606.ENSP00000299705

UniGene: Hs.513058

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