TBCC Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

Q15814
基因名：

TBCC
別名：

Beta tubulin cofactor C antibody; CFC antibody; TBCC antibody; TBCC_HUMAN antibody; Tubulin folding cofactor C antibody; Tubulin specific chaperone c antibody; Tubulin-folding cofactor C antibody; Tubulin-specific chaperone C antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human TBCC
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應用范圍：

ELISA,WB,IF
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Tubulin-folding protein; involved in the final step of the tubulin folding pathway.
基因功能參考文獻：
1. a testable model for TBCC N-terminal domain/tubulin recognition in which the highly charged N-terminus as well as residues from the three helices and the loops interact with the acidic hypervariable regions of tubulin monomers PMID: 22028797
2. Microtubule dynamicity was reduced in breast cancer cells overexpressing TBCC. Cell cycle distribution was altered in cells containing larger amounts of TBCC. TBCC had little effect on cell proliferation. PMID: 20384997
3. functional overlap with retinitis pigmenosa 2 protein PMID: 11847227
亞細胞定位：

Cytoplasm. Note=Detected predominantly in the photoreceptor connecting cilium.
蛋白家族：

TBCC family
組織特異性：

Expressed in the retina. Expressed in the rod and cone photoreceptors, extending from the inner segments (IS), through the outer nuclear layer (ONL) and into the synapses in the outer plexiform layer (OPL). Strongly expressed to the photoreceptor connecti
數(shù)據(jù)庫鏈接：

HGNC: 11580

OMIM: 602971

KEGG: hsa:6903

STRING: 9606.ENSP00000244625

UniGene: Hs.75064

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