TAF4B Antibody, Biotin conjugated
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中文名稱：TAF4B兔多克隆抗體, Biotin偶聯(lián)
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貨號(hào)：CSB-PA849782LD01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) TAF4B Polyclonal antibody
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Uniprot No.：
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基因名：TAF4B
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別名：TAF4B antibody; TAF2C2 antibody; TAFII105 antibody; Transcription initiation factor TFIID subunit 4B antibody; Transcription initiation factor TFIID 105 kDa subunit antibody; TAF(II)105 antibody; TAFII-105 antibody; TAFII105 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Transcription initiation factor TFIID subunit 4B protein (132-244AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Cell type-specific subunit of the general transcription factor TFIID that may function as a gene-selective coactivator in certain cells. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. TAF4B is a transcriptional coactivator of the p65/RELA NF-kappa-B subunit. Involved in the activation of a subset of antiapoptotic genes including TNFAIP3. May be involved in regulating folliculogenesis. Through interaction with OCBA/POU2AF1, acts as a coactivator of B-cell-specific transcription. Plays a role in spermiogenesis and oogenesis.
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基因功能參考文獻(xiàn)：
- The existence of a highly conserved TAF4b-dependent gene regulatory network. PMID: 27341508
- Two candidate loci in each family and homozygous truncating mutations p.R611X in TAF4B in family 1 and p.K507Sfs*3 in ZMYND15 in family 2, were identified. PMID: 24431330
- We show evidence for the first time of an interdependence of TAF4b and AP-1 family members in cell type-specific promoter recognition and initiation of transcription in the context of cancer progression and EMT. PMID: 20353996
- histone fold domain mediated interaction enhances the DNA binding activity of each of the TAF6-TAF9 and TAF4b-TAF12 pairs and of a histone-like octamer complex composed of the four TAFs PMID: 15601843
- work suggests that pre-mRNA processing and post-translational modification represent two important regulatory steps for the gonad-specific functions of human TAF(II)105 PMID: 16088961
- Expression of the TAF4b gene is induced by MYC through a non-canonical, but not canonical, E-box which contributes to its specific response to MYC. PMID: 19020761
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相關(guān)疾?。?/div>Spermatogenic failure 13 (SPGF13)亞細(xì)胞定位：Nucleus. Cytoplasm.蛋白家族：TAF4 family組織特異性：Preferentially expressed in ovarian granulosa cells (at protein level). Highly expressed in B-cells.數(shù)據(jù)庫鏈接：
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