SRSF6 Antibody
-
中文名稱：SRSF6兔多克隆抗體
-
貨號(hào)：CSB-PA021158GA01HU
-
規(guī)格：￥3,900
-
其他：
產(chǎn)品詳情
-
Uniprot No.：
-
基因名：SRSF6
-
別名：arginine/serine-rich 6 antibody; B52 antibody; Epididymis secretory protein Li 91 antibody; fc17h09 antibody; HEL S 91 antibody; MGC128807 antibody; MGC5045 antibody; Pre mRNA splicing factor SRP55 antibody; Pre-mRNA-splicing factor SRP55 antibody; Serine/arginine-rich splicing factor 6 antibody; SFRS6 antibody; Splicing factor antibody; Splicing factor arginine/serine rich 55 kDa antibody; Splicing factor arginine/serine rich 6 antibody; SR splicing factor 6 antibody; SRP55 antibody; SRSF6 antibody; SRSF6_HUMAN antibody; wu:faa54g02 antibody; wu:fc17h09 antibody; zgc:103497 antibody
-
宿主：Rabbit
-
反應(yīng)種屬：Human,Mouse,Rat
-
免疫原：Human SFRS6
-
免疫原種屬：Homo sapiens (Human)
-
抗體亞型：IgG
-
純化方式：Antigen Affinity Purified
-
濃度：It differs from different batches. Please contact us to confirm it.
-
保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
-
產(chǎn)品提供形式：Liquid
-
應(yīng)用范圍：ELISA,WB
-
Protocols：
-
儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
-
功能：Plays a role in constitutive splicing and modulates the selection of alternative splice sites. Plays a role in the alternative splicing of MAPT/Tau exon 10. Binds to alternative exons of TNC pre-mRNA and promotes the expression of alternatively spliced TNC. Plays a role in wound healing and in the regulation of keratinocyte differentiation and proliferation via its role in alternative splicing.
-
基因功能參考文獻(xiàn)：
- Data suggest that regulation of pancreatic beta-cell function and survival/apoptosis involves alternative splicing modulated by key splicing regulator SRP55; SRP55-regulated alternative splicing includes modulation of function of pro-apoptotic proteins (BIM, BAX), JNK signaling, and endoplasmic reticulum stress. (BIM = BCL-2 interacting protein BIM; BAX = apoptosis regulator BAX) PMID: 29246973
- The recent studies suggest that correcting the SRSF6-driven missplicing and/or microtubule-associated imbalance might be of therapeutic value in Huntington's disease. PMID: 27529534
- LINC01133 inhibits epithelial mesenchymal transformation and metastasis in colorectal neoplasms by directly binding to SRSF6 as a target mimic. PMID: 27443606
- SRSF6 is a regulator of wound healing and tissue homeostasis in skin. PMID: 24440982
- Zinc inhibits the activity of SRSF6 and promotes elimination of exon 4, leading to preferential generation of BimS. PMID: 23648111
- The splicing factor SRSF6 is an oncoprotein that regulates the proliferation and survival of lung and colon cancer cells. PMID: 23132731
- Phosphorylation of SRp55 by Dyrk1A suppressed its ability to promote Tau exon 10 inclusion. PMID: 22767602
- Report upregulation of Bim and the splicing factor SRp55 in melanoma cells from patients treated with selective BRAF inhibitors. PMID: 22516966
- SRp55 aids in the generation of partially spliced and unspliced HIV-1 mRNAs. PMID: 21345357
- interacts with calcitonin/CGRP exon 4 exonic splice enhancer(ESE); binding of SRp55 to an ESE required for calcitonin mRNA splicing suggests that the different levels of SRp55 in different cell types may regulate calcitonin/CGRP alternative splicing PMID: 12531473
- SRp55 binding to a suboptimal RNA binding site in the calcitonin/CGRP pre-mRNA exonic splice enhancer, or increasing the amount of SRp55 in cells, is required for calcitonin mRNA production. PMID: 12549914
- Higher relative expression of SR55 protein in breast tumors was associated with altered pattern of CD44 variants incorporating exon v7 PMID: 12779084
- These findings show that modulation of splicing activity in p53-deficient cells during the early response to sub-lethal DNA damage results in a change in the splicing of target genes, thus modifying the cellular response to genotoxic agents. PMID: 18571879
顯示更多
收起更多
-
亞細(xì)胞定位：Nucleus. Nucleus speckle.
-
蛋白家族：Splicing factor SR family
-
數(shù)據(jù)庫(kù)鏈接：
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
