SMPDL3A Antibody, HRP conjugated
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中文名稱：SMPDL3A兔多克隆抗體, HRP偶聯
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貨號：CSB-PA842119LB01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) SMPDL3A Polyclonal antibody
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Uniprot No.：
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基因名：SMPDL3A
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別名：SMPDL3A antibody; ASML3AAcid sphingomyelinase-like phosphodiesterase 3a antibody; ASM-like phosphodiesterase 3a antibody; EC 3.1.4.- antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Acid sphingomyelinase-like phosphodiesterase 3a protein (51-350AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：HRP
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Has in vitro nucleotide phosphodiesterase activity with nucleoside triphosphates, such as ATP. Has in vitro activity with p-nitrophenyl-TMP. Has lower activity with nucleoside diphosphates, and no activity with nucleoside monophosphates. Has in vitro activity with CDP-choline, giving rise to CMP and phosphocholine. Has in vitro activity with CDP-ethanolamine. Does not have sphingomyelin phosphodiesterase activity.
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基因功能參考文獻：
- Activation of pregnane X receptor induces SMPDL3A expression in primary hepatocytes. PMID: 28414139
- Site-specific N-glycosylation is essential for the intracellular stability, secretion and activity of human SMPDL3A. PMID: 28104755
- Solved the structure of SMPDL3a revealing a calcineurin-like fold. A dimetal site, glycosylation pattern and a disulfide bond network are likely to be conserved also in aSMase. We show that the binuclear site of SMPDL3a is occupied by two Zn(2+) ions. PMID: 26783088
- Data indicate that sphingomyelin phosphodiesterase acid-like 3A (SMPDL3A) is a nucleotide phosphodiesterase secreted from cholesterol-loaded macrophages. PMID: 25288789
- the induction of SMPDL3A is liver X receptor-dependent and is restricted to human blood cells with no induction observed in mouse cellular systems. PMID: 22810003
- ASML3a is involved in the process of bladder tumorigenesis PMID: 12442002
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亞細胞定位：Secreted.
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蛋白家族：Acid sphingomyelinase family
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組織特異性：Detected in blood serum. Detected in macrophages (at protein level).
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數據庫鏈接：
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