SMAD9 Antibody
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中文名稱：SMAD9兔多克隆抗體
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貨號：CSB-PA948873
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA948873(SMAD9 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA948873(SMAD9 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200) -
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: CSB-PA948873(SMAD9 Antibody) at dilution 1/290, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：MAD homolog 9 antibody; Madh6 antibody; Mothers against decapentaplegic antibody; Mothers against decapentaplegic homolog 9 antibody; Mothers against DPP homolog 9 antibody; SMAD 9 antibody; SMAD family member 9 antibody; SMAD, mothers against DPP homolog 9 (Drosophila) antibody; SMAD8A antibody; SMAD8B antibody; Smad9 antibody; SMAD9_HUMAN antibody
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Synthetic peptide of Human SMAD9
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:1000-1:2000 WB 1:200-1:1000 IHC 1:25-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD).
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基因功能參考文獻：
- Our results exclude a significant role for the SMAD9v90m mutation in juvenile polyposis syndrome PMID: 28424237
- Mutations in SMAD9 gene encoding for transforming growth factor (TGF)-[beta] superfamily have been identified in Pulmonary Arterial Hypertension. PMID: 28582316
- Phosphorylated Smad1/5/8/9 specifically bound to the BREs of Smad8/9 gene. The present study reveals that Smad8/9 is a unique R-Smad regulated through the BMP pathway at the mRNA level. PMID: 26748560
- Case Report: hamartomatous olyposis and gastrointestinal ganglioneuromas with SMAD9 germline mutation that reduces PTEN expression. PMID: 26122142
- ATP production by NaF promotes hypertrophy-like changes via activation of phospho-Smad8 PMID: 23384547
- CREBZF, a novel Smad8-binding protein. PMID: 22707059
- Study described the first mutation in SMAD8 in a patient with IPAH, and suggested the involvement of SMAD8 in the pathogenesis of PAH. PMID: 19211612
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相關疾病：Pulmonary hypertension, primary, 2 (PPH2)
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亞細胞定位：Cytoplasm. Nucleus.
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蛋白家族：Dwarfin/SMAD family
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組織特異性：Expressed in heart, brain, placenta, lung, skeletal muscle, prostate, testis, ovary and small intestine. Also expressed in fetal brain, lung and kidney.
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數據庫鏈接：
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