SLC35C1 Antibody, HRP conjugated
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中文名稱：SLC35C1兔多克隆抗體, HRP偶聯(lián)
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貨號(hào)：CSB-PA839285LB01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) SLC35C1 Polyclonal antibody
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Uniprot No.：
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基因名：SLC35C1
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別名：SLC35C1 antibody; FUCT1GDP-fucose transporter 1 antibody; Solute carrier family 35 member C1 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human GDP-fucose transporter 1 protein (287-364AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：HRP
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Involved in GDP-fucose import from the cytoplasm into the Golgi lumen.
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基因功能參考文獻(xiàn)：
- two Turkish siblings with a novel mutation in GDP-fucose transporter and features of congenital disorder of glycosylation IIc PMID: 25239688
- Fx enzyme and GDP-L-Fuc Tr overexpression in the tumur tissue of colorectal cancer (CRC) patients suggests that GDP-L-Fuc transport to the Golgi apparatus may be an important factor associated with increased alpha(1,6)fucosylation in CRC. PMID: 23730929
- In the rare LAD-II disease, the fucosylation of selectin ligands is disturbed, caused by mutations in SLC35C1, the gene that encodes a GDP-fucose transporter of the Golgi system. (Review) PMID: 22134107
- the conserved glycine residues at positions 180 and 277 of SLC35C1 have significant impacts on lectin binding PMID: 22492235
- In the GDP-fucose transporter a new single nucleotide deletion produced an open-reading frame shift & polypeptide truncation. Overexpression of the mutant protein in fibroblasts did not rescue fucosylation. The deletion ablated transporter activity. PMID: 12406889
- Leukocyte adhesion deficiency II patients display dual defect in functoin ang Golgi expression of FUCT1. PMID: 16455955
- the upregulation of GDP-Fuc Tr plays a pivotal role in increased fucosylation in hepatocellular carcinoma PMID: 17884843
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相關(guān)疾病：Congenital disorder of glycosylation 2C (CDG2C)
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亞細(xì)胞定位：Golgi apparatus membrane; Multi-pass membrane protein.
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蛋白家族：TPT transporter family, SLC35C subfamily
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數(shù)據(jù)庫(kù)鏈接：
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