The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA143150(SLC27A2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
ACSVL1 antibody; FACVL1 antibody; FATP 2 antibody; FATP-2 antibody; FATP2 antibody; Fatty acid coenzyme A ligase, very long chain 1 antibody; Fatty acid transport protein 2 antibody; Fatty-acid-coenzyme A ligase antibody; hFACVL1 antibody; HsT17226 antibody; Long chain fatty acid CoA ligase antibody; Long-chain-fatty-acid--CoA ligase antibody; S27A2_HUMAN antibody; Slc27a2 antibody; Solute carrier family 27 (fatty acid transporter), member 2 antibody; Solute carrier family 27 member 2 antibody; THCA CoA ligase antibody; THCA-CoA ligase antibody; Very long chain acyl CoA synthetase antibody; Very long chain fatty acid CoA ligase antibody; Very long chain fatty acid coenzyme A ligase 1 antibody; very long-chain 1 antibody; Very long-chain acyl-CoA synthetase antibody; Very long-chain-fatty-acid-CoA ligase antibody; VLACS antibody; VLCS antibody
宿主:
Rabbit
反應種屬:
Human,Mouse,Rat
免疫原:
Fusion protein of Human SLC27A2
免疫原種屬:
Homo sapiens (Human)
標記方式:
Non-conjugated
抗體亞型:
IgG
純化方式:
Antigen affinity purification
濃度:
It differs from different batches. Please contact us to confirm it.
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
Acyl CoA synthetase that activates long-chain and very long-chain fatty acids (VLCFAs) by catalyzing the formation of fatty acyl-CoA. Can also activate branched-chain fatty acids such as phytanic acid and pristanic acid. Does not activate C24 bile acids, cholate and chenodeoxycholate. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Exhibits long-chain fatty acids (LCFA) transport activity and plays an important role in hepatic fatty acid uptake.; Exhibits both long-chain fatty acids (LCFA) transport activity and acyl CoA synthetase towards very long-chain fatty acids. Shows a preference for generating CoA derivatives of n-3 fatty acids, which are preferentially trafficked into phosphatidylinositol.; Exhibits long-chain fatty acids (LCFA) transport activity but lacks acyl CoA synthetase towards very long-chain fatty acids.
基因功能參考文獻:
In overweight/obese pregnancies, the increased FATP2 placental expression could contribute to increased fatty acid delivery to the fetus. PMID: 27016784
In mice Grassofermata decreased absorption of (13)C-oleate demonstrating its potential as a therapeutic agent. PMID: 26284975
Protective effects of breastfeeding are reflected in higher expression levels of SLC27A2, FASN, PPARalpha and INSR in blood cells. PMID: 24277691
these data support the conclusion that FATP2 has a dual function in the pathways linking the transport and activation of exogenous fatty acids. PMID: 24113382
FATP2a functions in fatty acid transport and activation and provides specificity toward n-3 fatty acids in which the corresponding n-3 acyl-CoAs are preferentially trafficked into acyl-CoA pools destined for phosphatidylinositol incorporation PMID: 21768100